Q6YQX2 · PNP_ONYPE

Function

function

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

1715100200300400500600700
TypeIDPosition(s)Description
Binding site498Mg2+ (UniProtKB | ChEBI)
Binding site504Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5'-RNA exonuclease activity
Molecular Functionmagnesium ion binding
Molecular Functionpolyribonucleotide nucleotidyltransferase activity
Molecular FunctionRNA binding
Biological ProcessmRNA catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyribonucleotide nucleotidyltransferase
  • EC number
  • Alternative names
    • Polynucleotide phosphorylase
      (PNPase
      )

Gene names

    • Name
      pnp
    • Ordered locus names
      PAM_251

Organism names

Accessions

  • Primary accession
    Q6YQX2

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003297451-715Polyribonucleotide nucleotidyltransferase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain565-625KH
Domain635-706S1 motif

Sequence similarities

Belongs to the polyribonucleotide nucleotidyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    715
  • Mass (Da)
    80,121
  • Last updated
    2004-07-05 v1
  • Checksum
    F77537184C982E9B
MLKKVFETTNLKDSFQVEIGTYARNVDASILVRYQDTVVLTTTVFSRKPNNLDFLPLTVIYQEKLYAAGKIPGSFLRREGRSNDHEILTSRLIDRSLRPLFPDYFQQEVQVINTVLSLDPDFKSELASMLGSSLSLLISEIPFFEAISGVYVGKINDKFIINPTLQQLANSTLHLMVAGTKHNVTMIEAHANEVSEQDFLEAINFAHQYIKKLCLFQENIKQQFAPAKITNTLHQTEQTQQQAFFAKHQSQVKQAILSCNSKNDLQQLKEQILDQAKQTPFFKTIDTATVFDYEAHKKHLQTTETLFQKLSKQETRSLILQEKIRPDKRGLEEIRTLESQIDLLPRAHGSALFTRGQTQSLAAVTLGCLSESKIIDGLSDEQNKRFMLHYNFPPFSVGAVGRYTAPSRREIGHGTLAEKAISQVLPEEKDFPYTIRVVSEILESNGSSSQATVCASSLALMASGVPLKKAVAGMSVGLVFDQATNKYVILSDIQGLEDHVGDMDLKIAGTNKGITALQMDLKIQGIHFKILQEAFLQAKKGRLHILEHMSQTISQPRLEVSKYAPKVCMMQIKPEKIRDIIGSGGKIINQIIESHDGVKIDIEQDGRVFVMHSNLETVKKTVAFIESLIQEIQIGTCYQASILRFLSDKQGKMIGAVAQVCPGIEGLIHVNQKKFQKITDVLKIGETVSVKCTKINDRGRIDFLLLPKNTQEKNS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP006628
EMBL· GenBank· DDBJ
BAD04336.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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