Q6YL54 · Q6YL54_PRUPE
- ProteinDNA (cytosine-5)-methyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1564 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 1229 | |||||
Sequence: C |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | chromatin binding | |
Molecular Function | DNA (cytosine-5-)-methyltransferase activity | |
Molecular Function | DNA binding | |
Biological Process | DNA methylation-dependent heterochromatin formation | |
Biological Process | methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameDNA (cytosine-5)-methyltransferase
- EC number
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Rosales > Rosaceae > Amygdaloideae > Amygdaleae > Prunus
Accessions
- Primary accessionQ6YL54
Subcellular Location
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 16-81 | Disordered | ||||
Sequence: LEAKGANGTKPPSSSSSGMTKKKKGKQDSQKAAPKAKKRNLPQSSEEEPSRSRKMPKRAAACKDFK | ||||||
Compositional bias | 36-81 | Basic and acidic residues | ||||
Sequence: KKKKGKQDSQKAAPKAKKRNLPQSSEEEPSRSRKMPKRAAACKDFK | ||||||
Region | 683-730 | Disordered | ||||
Sequence: YSPEDSKEGDIGEKKEEEEVEEEDVEEDDVEENPTVMEQAQKPSSISR | ||||||
Compositional bias | 697-716 | Acidic residues | ||||
Sequence: KEEEEVEEEDVEEDDVEENP | ||||||
Domain | 766-900 | BAH | ||||
Sequence: EEISVGGAVLVELDESHELPAIYFVEYMYETLNGSKMFHGRVMERGSQTVLGNTANEREVFLTNECTNLALKEVKQAAAVGIKVMPWGHQYRKDNADANRTDRARAEERKRKGLPTEYYCKSLYCPERGAFLSLS | ||||||
Domain | 940-1080 | BAH | ||||
Sequence: VEYSVHDYVYVSPHYFGVERMETEIFKAGRNLVLKAYVVCQVLEIVVMKESKRPEIESTQVKVRRFFRPEDISVEKAYSSDIREVYYSEQTHIVPVDNIERKCEVRKKSDLPVCNAPVIFQHIFFCEHLYDPSKGSIKQLP | ||||||
Region | 1089-1111 | Disordered | ||||
Sequence: TGGGHADSRKRKGKCKEGENVSE | ||||||
Compositional bias | 1091-1111 | Basic and acidic residues | ||||
Sequence: GGHADSRKRKGKCKEGENVSE |
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,564
- Mass (Da)175,215
- Last updated2004-07-05 v1
- Checksum81C47C55217F3847
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 36-81 | Basic and acidic residues | ||||
Sequence: KKKKGKQDSQKAAPKAKKRNLPQSSEEEPSRSRKMPKRAAACKDFK | ||||||
Compositional bias | 697-716 | Acidic residues | ||||
Sequence: KEEEEVEEEDVEEDDVEENP | ||||||
Compositional bias | 1091-1111 | Basic and acidic residues | ||||
Sequence: GGHADSRKRKGKCKEGENVSE |