Q6W102 · KATG_SINFN
- ProteinCatalase-peroxidase
- GenekatG
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids718 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
Catalytic activity
- AH2 + H2O2 = A + 2 H2O
Cofactor
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
Features
Showing features for site, active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | catalase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | response to oxidative stress |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameCatalase-peroxidase
- EC number
- Short namesCP
- Alternative names
Gene names
Encoded on
- Plasmid sym pNGR234b
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Sinorhizobium/Ensifer group > Sinorhizobium
Accessions
- Primary accessionQ6W102
- Secondary accessions
Proteomes
PTM/Processing
Features
Showing features for chain, cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000354888 | 1-718 | Catalase-peroxidase | |||
Sequence: MDQKSDNAGKCPVAHTVPKGRSNRDWWPDQLDVQVLHQHSGLSDPMGKAFNYAEEFKKLDLEELKKDLHALMTESQDWWPADFGHYGGLFIRMAWHSAGTYRITDGRGGAGQGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGNRISWADLMILTGNVALESMGFQTFGFAGGRADVWEPQELFWGPEGTWLGDERYSGERQLDEPLAAVQMGLIYVNPEGPNGNPDPVAAAREIRETFARMAMNDEETVALIAGGHTFGKTHGAGDPSFIGPDPEGGAIEDQGLGWKSTFGTGVGKDAITGGPEVTWSQTPTRWSNYFFENLFNYEWELTKSPAGAHQWKAKNADASIPDAFDASKKHVPTMLTTDLSLRFDPIYEKISRRFLENPDQFADAFARAWFKLTHRDMGPKVRYLGPEVPAEDLIWQDVIPAVDHKLVDENDVADLKGKVLASGLSVQELVSTAWASASTFRGSDKRGGANGARIRLAPQKDWEVNQPAQLARVLSVLEGIQKDFNTAHTGGKKISLADLIVLAGAAGVEKAAKAGGHDITVPFTPGRADASEAQTDAASFAALEPRADGFRNYVSRRRRQFMKPEEALVDRAQLLTLTAPELTVLVGGLRVVFTSRPEVLTNDFFVNLLDMGTQWSPMAEKEGVYEGRDRKTHEVKWTGTRVDLIFGSHSQLRALAEVYASSDAKEKFVGDFVAAWTKVMNADRFDLV | ||||||
Cross-link | 95↔217 | Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-243) | ||||
Sequence: WHSAGTYRITDGRGGAGQGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGNRISWADLMILTGNVALESMGFQTFGFAGGRADVWEPQELFWGPEGTWLGDERYSGERQLDEPLAAVQMGLIY | ||||||
Cross-link | 217↔243 | Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-95) | ||||
Sequence: YVNPEGPNGNPDPVAAAREIRETFARM |
Post-translational modification
Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
Interaction
Subunit
Homodimer or homotetramer.
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-24 | Disordered | ||||
Sequence: MDQKSDNAGKCPVAHTVPKGRSNR |
Sequence similarities
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length718
- Mass (Da)79,396
- Last updated2009-07-07 v3
- Checksum7FE0DE1975427F41
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY316747 EMBL· GenBank· DDBJ | AAQ87566.1 EMBL· GenBank· DDBJ | Genomic DNA | Frameshift | |
CP000874 EMBL· GenBank· DDBJ | ACP22099.1 EMBL· GenBank· DDBJ | Genomic DNA | Frameshift |