Q6V9D6 · CYB_TALMA
- ProteinCytochrome b
- Genecob
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids386 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Miscellaneous
Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
Cofactor
Note: Binds 2 heme b groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 82 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 96 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 183 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 197 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 202 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | mitochondrial electron transport, ubiquinol to cytochrome c |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
- Alternative names
Gene names
Encoded on
- Mitochondrion
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Trichocomaceae > Talaromyces > Talaromyces sect. Talaromyces
Accessions
- Primary accessionQ6V9D6
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 32-52 | Helical | ||||
Sequence: FGSLLALCLIIQIVTGVTLAM | ||||||
Transmembrane | 76-98 | Helical | ||||
Sequence: WLIRYLHANTASAFFFLVYLHVG | ||||||
Transmembrane | 113-133 | Helical | ||||
Sequence: TWIIGSIILIVMMATAFLGYV | ||||||
Transmembrane | 179-199 | Helical | ||||
Sequence: FFALHFVLPFVLAALVIMHLI | ||||||
Transmembrane | 226-246 | Helical | ||||
Sequence: YIFKDLITIFLFFFVLSLFVF | ||||||
Transmembrane | 290-310 | Helical | ||||
Sequence: LLGVIAMFSAILIILVMPITD | ||||||
Transmembrane | 322-342 | Helical | ||||
Sequence: LSKVAFYVFVANFLILMQLGA | ||||||
Transmembrane | 349-369 | Helical | ||||
Sequence: FIEFGQISTVLYFSHFLVIMP |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000061750 | 1-386 | Cytochrome b | |||
Sequence: MRIFKSHPLLRLVNSYVIDSPTPSNLSYLWNFGSLLALCLIIQIVTGVTLAMHYTPSVAEAFNSVEHIMRDVNNGWLIRYLHANTASAFFFLVYLHVGRGIYYGSYKAPRTLTWIIGSIILIVMMATAFLGYVLPYGQMSLWGATVITNLMSAIPWIGQDIVEFLWGGFSVNNATLNRFFALHFVLPFVLAALVIMHLISYHETVGSGNPLGISSNYDRLPFAPYYIFKDLITIFLFFFVLSLFVFFMPNALGDSENYVMANPMQTPPAIVPEWYLLPFYAILRSIPNKLLGVIAMFSAILIILVMPITDLSKYRGLQFRPLSKVAFYVFVANFLILMQLGAKHVESPFIEFGQISTVLYFSHFLVIMPLVSFIENTLVELITKKS |
Interaction
Subunit
Fungal cytochrome b-c1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins. Cytochrome b-c1 complex is a homodimer.
Structure
Sequence
- Sequence statusComplete
- Length386
- Mass (Da)43,689
- Last updated2004-07-05 v1
- Checksum2180F36F4EC840EE
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY347307 EMBL· GenBank· DDBJ | AAQ54914.1 EMBL· GenBank· DDBJ | Genomic DNA |