Q6V9D6 · CYB_TALMA

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.

Caution

The protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme b groups non-covalently.

Features

Showing features for binding site.

138650100150200250300350
TypeIDPosition(s)Description
Binding site82Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site96Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site183Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site197Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site202a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial respiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b
  • Alternative names
    • Complex III subunit 3
    • Complex III subunit III
    • Cytochrome b-c1 complex subunit 3
    • Ubiquinol-cytochrome-c reductase complex cytochrome b subunit

Gene names

    • Name
      cob
    • Synonyms
      cytB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strain
    • MP1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Trichocomaceae > Talaromyces > Talaromyces sect. Talaromyces

Accessions

  • Primary accession
    Q6V9D6

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane32-52Helical
Transmembrane76-98Helical
Transmembrane113-133Helical
Transmembrane179-199Helical
Transmembrane226-246Helical
Transmembrane290-310Helical
Transmembrane322-342Helical
Transmembrane349-369Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000617501-386Cytochrome b

Interaction

Subunit

Fungal cytochrome b-c1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins. Cytochrome b-c1 complex is a homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    386
  • Mass (Da)
    43,689
  • Last updated
    2004-07-05 v1
  • Checksum
    2180F36F4EC840EE
MRIFKSHPLLRLVNSYVIDSPTPSNLSYLWNFGSLLALCLIIQIVTGVTLAMHYTPSVAEAFNSVEHIMRDVNNGWLIRYLHANTASAFFFLVYLHVGRGIYYGSYKAPRTLTWIIGSIILIVMMATAFLGYVLPYGQMSLWGATVITNLMSAIPWIGQDIVEFLWGGFSVNNATLNRFFALHFVLPFVLAALVIMHLISYHETVGSGNPLGISSNYDRLPFAPYYIFKDLITIFLFFFVLSLFVFFMPNALGDSENYVMANPMQTPPAIVPEWYLLPFYAILRSIPNKLLGVIAMFSAILIILVMPITDLSKYRGLQFRPLSKVAFYVFVANFLILMQLGAKHVESPFIEFGQISTVLYFSHFLVIMPLVSFIENTLVELITKKS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY347307
EMBL· GenBank· DDBJ
AAQ54914.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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