Q6TLF9 · Q6TLF9_DANRE

Function

function

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentclathrin adaptor complex
Cellular Componentcytoplasmic vesicle
Cellular ComponentGolgi apparatus
Biological Processendocytosis
Biological Processintracellular protein transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    AP-3 complex subunit mu-1
  • Alternative names
    • AP-3 adaptor complex mu3A subunit
    • Adaptor-related protein complex 3 subunit mu-1
    • Mu-adaptin 3A
    • Mu3A-adaptin

Gene names

    • Name
      ap3m1
    • Synonyms
      cb430

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q6TLF9

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain176-420MHD
Region351-375Disordered

Sequence similarities

Belongs to the adaptor complexes medium subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    421
  • Mass (Da)
    47,607
  • Last updated
    2004-07-05 v1
  • Checksum
    4E046CECF9E250E5
MIHSLFLINNVGDLFLEKHWKSVISRSVCDYFFEAREKAGEPDNVPPVIRTPHHYLINIYRDKIFFVSVIQTEVPPLFVIEFLHRVAETFQDYFGECSEMTIKENMVIVYELLEEMLDNGFPLATESNILKELIRPPNILRTMVNTITGSSNVGETLPTGQLSTIPWRRAGVKYTNNEAYFDVVEEIDAILDKSGTTVFAEIQGVIDACVKLSGMPDLTLSFMNPRLLDDVSFHPCVRYKRWESERVISFIPPDGNFQLMSYHISAQNLVAIPVYVKQNISFFESGSSGRLDITVSPKQTMGKVVECVVVTIHMPKVVLSATLNATQGTYKYDPLTKILVWDIGKLNPQNTQKQPNLKGSLSLQSGAPKPEENPSLNIDLKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A9JRS9A9JRS9_DANREap3m1421

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC128809
EMBL· GenBank· DDBJ
AAI28810.1
EMBL· GenBank· DDBJ
mRNA
AY394946
EMBL· GenBank· DDBJ
AAQ94573.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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