Q6PFU9 · Q6PFU9_DANRE
- ProteinA disintegrin and metalloproteinase domain 17a
- Geneadam17a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids842 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 414 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 415 | ||||
Binding site | 418 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 424 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | integrin-mediated signaling pathway | |
Biological Process | membrane protein ectodomain proteolysis | |
Biological Process | Notch signaling pathway |
Keywords
- Molecular function
- Biological process
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ6PFU9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 679-701 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-18 | ||||
Chain | PRO_5035035857 | 19-842 | |||
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 233-483 | Peptidase M12B | |||
Domain | 484-572 | Disintegrin | |||
Region | 743-842 | Disordered | |||
Compositional bias | 783-806 | Basic and acidic residues | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length842
- Mass (Da)94,161
- Last updated2004-07-05 v1
- MD5 Checksum47847B675AC26D6F1BA69495BF588155
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2R8Q3V6 | A0A2R8Q3V6_DANRE | adam17a | 848 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 783-806 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC057410 EMBL· GenBank· DDBJ | AAH57410.1 EMBL· GenBank· DDBJ | mRNA |