Q6PFU9 · Q6PFU9_DANRE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for binding site, active site.

1842100200300400500600700800
Type
IDPosition(s)Description
Binding site414Zn2+ (UniProtKB | ChEBI); catalytic
Active site415
Binding site418Zn2+ (UniProtKB | ChEBI); catalytic
Binding site424Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processintegrin-mediated signaling pathway
Biological Processmembrane protein ectodomain proteolysis
Biological ProcessNotch signaling pathway

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Submitted names
    • A disintegrin and metalloproteinase domain 17a
    • ADAM metallopeptidase domain 17a precursor

Gene names

    • Name
      adam17a
    • Synonyms
      fc20b01
      , wu:fc20b01
      , zgc:63886

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q6PFU9

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane679-701Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-18
ChainPRO_503503585719-842

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain233-483Peptidase M12B
Domain484-572Disintegrin
Region743-842Disordered
Compositional bias783-806Basic and acidic residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    842
  • Mass (Da)
    94,161
  • Last updated
    2004-07-05 v1
  • MD5 Checksum
    47847B675AC26D6F1BA69495BF588155
MKPCIFYLVLLAPLFAHCAVKPVSVEEVSRNEEELQEFDALNSLLSDFEVLPASGLQLHSVRKRDADAHSHVERLVSFTALQRNFKLYLTTNTQLFTENFSAVFVDENGKEDQFDVQIQNYFKGHVVGEEHSRVQAHIDGDEFSAHIITEETEYNVEPLWRFTETPPDGRLLVYRSEDIKNISRLSSPKVCGYVNADAQELLPEEARAAEEMEEMKEEPHNRERRSTHDQKKNTCTLLLVADHRFYKHMGRAEESTTLNYLIELIDRVDDIYRNTSWDDDFKGYGVQIQQIIINKDPTKVAPGEFHYNMDGSPTGRKDGVWDVKKLLEQFSYDIAANASRACLAHLFTYQDFDDGTLGLAYVAPSKPGLGGLCPKPYYPSQSVKKPSYLNTGLTSTMNYGKTILTKEADLVTTHELGHNFGAEHDPDNIASCAPSDDQGGKYVMYPIAVSGDHVNNKHFSTCSKISVSKTLRIKVNQCFVERSSKLCGNSRVEEDEDCDPGLLHINDDPCCTSNCKFRKQAQCSDRNSPCCKNCMFESADKVCQEVITATCKGTSQCTGNSSECPTPGNLEDNTECVDKGRCQNGQCRPFCEAVHNLESCACNETENSCKVCCRKDELCTPFLNGGSFLYLRKGKPCTVGFCDGAGKCMKQVQDVIERLWDFIDKLNINTFGKFLADNIVGSVVVFSLLFWIPISILVHCVDKRLDEQYEENTKMMYPSSGEILSSLESVPVRIFKAHHVHSPAARPQLSMAPTGPGSTPAQETLGGPGHPSLSAAPKADQLRMATIEEDPSGDSFHPDEEEGFRLSGTAARSFEDLTEQATPSHKRRLKRQARIESKETEC

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2R8Q3V6A0A2R8Q3V6_DANREadam17a848

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias783-806Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC057410
EMBL· GenBank· DDBJ
AAH57410.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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