Q6PF62 · Q6PF62_XENLA
- ProteinPhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- Genepck1.S
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids622 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- L-seryl-[protein] + GTP = O-phospho-L-seryl-[protein] + GDP + H+This reaction proceeds in the forward direction.
Cofactor
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | GTP binding | |
Molecular Function | kinase activity | |
Molecular Function | manganese ion binding | |
Molecular Function | phosphoenolpyruvate carboxykinase (GTP) activity | |
Biological Process | cellular response to dexamethasone stimulus | |
Biological Process | cellular response to glucose stimulus | |
Biological Process | cellular response to insulin stimulus | |
Biological Process | dicarboxylic acid metabolic process | |
Biological Process | gluconeogenesis | |
Biological Process | glycerol biosynthetic process from pyruvate | |
Biological Process | hepatocyte differentiation | |
Biological Process | phosphorylation | |
Biological Process | propionate catabolic process | |
Biological Process | response to starvation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus
Accessions
- Primary accessionQ6PF62
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 30-256 | Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal | |||
Domain | 260-617 | Phosphoenolpyruvate carboxykinase C-terminal P-loop | |||
Sequence similarities
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length622
- Mass (Da)69,862
- Last updated2004-07-05 v1
- Checksum2EC83C08EF0897C3
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC057715 EMBL· GenBank· DDBJ | AAH57715.1 EMBL· GenBank· DDBJ | mRNA |