Q6PE30 · Q6PE30_DANRE

Function

Catalytic activity

  • Exonucleolytic cleavage of poly(A) to 5'-AMP.
    EC:3.1.13.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentCCR4-NOT complex
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functionmetal ion binding
Molecular Functionpoly(A)-specific ribonuclease activity
Biological Processnuclear-transcribed mRNA poly(A) tail shortening
Biological Processregulatory ncRNA-mediated gene silencing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    poly(A)-specific ribonuclease
  • EC number

Gene names

    • Name
      cnot6a
    • Synonyms
      cnot6
      , wu:fa03c11
      , wu:fc17f01
      , zgc:65822

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q6PE30
  • Secondary accessions
    • A0A8M3AU38

Proteomes

    • Identifier
    • Component
      Alternate scaffold 21, Chromosome 21

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain192-531Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the CCR4/nocturin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    557
  • Mass (Da)
    63,037
  • Last updated
    2004-07-05 v1
  • Checksum
    0AD84B05F3E2D17B
MPKEKYDPPDPRRMYTIMSSEEAANGKKSTWAELEIVGKVKSLSSALWSLTHLTALYISDNSLSRIPPDIAKLNNLVYLDLSSNKIRSLPAELGNMINLRELLLNNNQLRVLPFELGKLFQLQTLGLKGNPLAQEILNLYQEPDGTRRLLNYLLDNLAGTKRAPIEQPPPRSWIPLQEPDRTRPAALFSVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKSIMQEILSCSADIISLQEVETEQYYNYFLLELKEQGYEGFFSPKSRARTMSESDRKHVDGCAVFYKTDKFSLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKEMMELSAGKPLHGMEKQLLLVANAHMHWDPEYSDVKLVQTMMFLSEVKNIVDKATRSLKLSSVSGETNAIPLVLCADLNSLPDSGVVEYLSTGGVDGAHKDFKELRYIDSLTNFNCNGKNGTSSTRITHGFKLKSAYENGLMPYTNYTFDFKGIIDYIFYSQPLLNVLGVLGPLEHHWLLENNVTGCPHPHIPSDHFSLFAQLELLLPFPPAVNGIHLPGRR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX511225
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC058309
EMBL· GenBank· DDBJ
AAH58309.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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