Q6PD18 · Q6PD18_MOUSE
- ProteinAdamts7 protein
- GeneAdamts7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1361 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 61 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 61 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 68 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 120 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Active site | 121 | |||||
Sequence: E | ||||||
Binding site | 124 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 130 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 180 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 183 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 183 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | extracellular matrix organization | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ6PD18
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 50↔104 | |||||
Sequence: CRWQKNINIKGDDHPQHHDTAILLTRKDLCASMNQPCETLGLSHVSGLCHPQLSC | ||||||
Disulfide bond | 79↔86 | |||||
Sequence: CASMNQPC | ||||||
Disulfide bond | 98↔180 | |||||
Sequence: CHPQLSCSVSEDTGMPLAFTVAHELGHSFGIQHDGTGNDCESIGKRPFIMSPQLLYDRGIPLTWSRCSREYITRFLDRGWGLC | ||||||
Disulfide bond | 137↔164 | |||||
Sequence: CESIGKRPFIMSPQLLYDRGIPLTWSRC | ||||||
Disulfide bond | 207↔230 | |||||
Sequence: CRLQYGSHSAYCEDMDDVCHTLWC | ||||||
Disulfide bond | 218↔236 | |||||
Sequence: CEDMDDVCHTLWCSVGTTC | ||||||
Disulfide bond | 225↔255 | |||||
Sequence: CHTLWCSVGTTCHSKLDAAVDGTSCGKNKWC | ||||||
Disulfide bond | 249↔260 | |||||
Sequence: CGKNKWCLKGEC | ||||||
Disulfide bond | 283↔320 | |||||
Sequence: CSRSCGVGVRSSERQCTQPVPKNRGKYCVGERKRSQLC | ||||||
Disulfide bond | 287↔325 | |||||
Sequence: CGVGVRSSERQCTQPVPKNRGKYCVGERKRSQLCNLPAC | ||||||
Disulfide bond | 298↔310 | |||||
Sequence: CTQPVPKNRGKYC |
Keywords
- PTM
Proteomic databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-185 | Peptidase M12B | ||||
Sequence: TIMNMVAGLFHDPSIGNPIHISIVRLIILEDEEKDLKITHHAEETLKNFCRWQKNINIKGDDHPQHHDTAILLTRKDLCASMNQPCETLGLSHVSGLCHPQLSCSVSEDTGMPLAFTVAHELGHSFGIQHDGTGNDCESIGKRPFIMSPQLLYDRGIPLTWSRCSREYITRFLDRGWGLCLDDRP | ||||||
Region | 714-734 | Disordered | ||||
Sequence: APRPSPASSPKPVSISNAIDE | ||||||
Region | 777-831 | Disordered | ||||
Sequence: GGWTAPPHIRPTESPSDTPVPTAGALGAEAEDIQGSWSPSPLLSEASYSPPGLEQ | ||||||
Compositional bias | 813-831 | Polar residues | ||||
Sequence: WSPSPLLSEASYSPPGLEQ | ||||||
Region | 844-941 | Disordered | ||||
Sequence: EDTPMGAPELGFPSLPWPPASVDDMMTPVGPGNPDELLVKEDEQSPPSTPWSDRNKLSTDGNPLGHTSPALPQSPIPTQPSPPSISPTQASPSPDVVE | ||||||
Compositional bias | 888-915 | Polar residues | ||||
Sequence: SPPSTPWSDRNKLSTDGNPLGHTSPALP | ||||||
Compositional bias | 916-932 | Pro residues | ||||
Sequence: QSPIPTQPSPPSISPTQ | ||||||
Region | 987-1008 | Disordered | ||||
Sequence: GRDSPLEPGTPTFSSPELSSQH | ||||||
Compositional bias | 994-1008 | Polar residues | ||||
Sequence: PGTPTFSSPELSSQH | ||||||
Region | 1021-1088 | Disordered | ||||
Sequence: TVPTDLRSPGPSGQPQTPNLEGTQSPGLLPTPARETQTNSSKDPEVQPLQPSLEEDGDPADPLPARNA | ||||||
Compositional bias | 1027-1067 | Polar residues | ||||
Sequence: RSPGPSGQPQTPNLEGTQSPGLLPTPARETQTNSSKDPEVQ | ||||||
Domain | 1307-1347 | PLAC | ||||
Sequence: EPPRCERDRLSFNFCETLRLLGRCQLPTIRAQCCRSCPPLS |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,361
- Mass (Da)149,550
- Last updated2004-07-05 v1
- Checksum49D04B6A28AFA877
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: T | ||||||
Compositional bias | 813-831 | Polar residues | ||||
Sequence: WSPSPLLSEASYSPPGLEQ | ||||||
Compositional bias | 888-915 | Polar residues | ||||
Sequence: SPPSTPWSDRNKLSTDGNPLGHTSPALP | ||||||
Compositional bias | 916-932 | Pro residues | ||||
Sequence: QSPIPTQPSPPSISPTQ | ||||||
Compositional bias | 994-1008 | Polar residues | ||||
Sequence: PGTPTFSSPELSSQH | ||||||
Compositional bias | 1027-1067 | Polar residues | ||||
Sequence: RSPGPSGQPQTPNLEGTQSPGLLPTPARETQTNSSKDPEVQ |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC058991 EMBL· GenBank· DDBJ | AAH58991.1 EMBL· GenBank· DDBJ | mRNA |