Q6PCP3 · Q6PCP3_MOUSE
- Proteinprotein-serine/threonine phosphatase
- GeneDusp16
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids660 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
rs3388847580 | 2 | A>T | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134738033C>T Codon: GCC/ACC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134738033C>T Locations: - p.Ala2Thr (Ensembl:ENSMUST00000100857) - c.4G>A (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388862950 | 5 | M>I | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.16) Somatic: No Accession: NC_000072.7:g.134738022C>T Codon: ATG/ATA Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134738022C>T Locations: - p.Met5Ile (Ensembl:ENSMUST00000100857) - c.15G>A (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388860133 | 9 | Q>H | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134738010T>G Codon: CAA/CAC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134738010T>G Locations: - p.Gln9His (Ensembl:ENSMUST00000100857) - c.27A>C (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388859498 | 42 | I>N | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134737912A>T Codon: ATT/AAT Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134737912A>T Locations: - p.Ile42Asn (Ensembl:ENSMUST00000100857) - c.125T>A (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388843696 | 106 | V>I | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.57) Somatic: No Accession: NC_000072.7:g.134735633C>T Codon: GTA/ATA Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134735633C>T Locations: - p.Val106Ile (Ensembl:ENSMUST00000100857) - c.316G>A (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388851950 | 166 | L>P | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134716809A>G Codon: CTC/CCC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134716809A>G Locations: - p.Leu166Pro (Ensembl:ENSMUST00000100857) - c.497T>C (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388868864 | 200 | F>L | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134702892A>G Codon: TTC/CTC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134702892A>G Locations: - p.Phe200Leu (Ensembl:ENSMUST00000100857) - c.598T>C (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388865969 | 222 | W>C | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134702824C>G Codon: TGG/TGC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134702824C>G Locations: - p.Trp222Cys (Ensembl:ENSMUST00000100857) - c.666G>C (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388865986 | 237 | N>I | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134697562T>A Codon: AAT/ATT Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134697562T>A Locations: - p.Asn237Ile (Ensembl:ENSMUST00000100857) - c.710A>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388862871 | 284 | N>D | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134695980T>C Codon: AAT/GAT Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695980T>C Locations: - p.Asn284Asp (Ensembl:ENSMUST00000100857) - c.850A>G (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388862869 | 286 | N>I | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134695973T>A Codon: AAT/ATT Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695973T>A Locations: - p.Asn286Ile (Ensembl:ENSMUST00000100857) - c.857A>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388850364 | 291 | L>F | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134695959G>A Codon: CTC/TTC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695959G>A Locations: - p.Leu291Phe (Ensembl:ENSMUST00000100857) - c.871C>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388843693 | 308 | K>M | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: NC_000072.7:g.134695907T>A Codon: AAG/ATG Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695907T>A Locations: - p.Lys308Met (Ensembl:ENSMUST00000100857) - c.923A>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388856220 | 347 | E>V | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: NC_000072.7:g.134695790T>A Codon: GAG/GTG Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695790T>A Locations: - p.Glu347Val (Ensembl:ENSMUST00000100857) - c.1040A>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388843703 | 356 | P>H | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: NC_000072.7:g.134695763G>T Codon: CCT/CAT Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695763G>T Locations: - p.Pro356His (Ensembl:ENSMUST00000100857) - c.1067C>A (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388862955 | 394 | R>C | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: NC_000072.7:g.134695650G>A Codon: CGT/TGT Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695650G>A Locations: - p.Arg394Cys (Ensembl:ENSMUST00000100857) - c.1180C>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388850322 | 406 | S>L | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: NC_000072.7:g.134695613G>A Codon: TCA/TTA Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695613G>A Locations: - p.Ser406Leu (Ensembl:ENSMUST00000100857) - c.1217C>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388847559 | 408 | S>I | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.07) Somatic: No Accession: NC_000072.7:g.134695607C>A Codon: AGT/ATT Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695607C>A Locations: - p.Ser408Ile (Ensembl:ENSMUST00000100857) - c.1223G>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388868841 | 415 | G>V | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.08) Somatic: No Accession: NC_000072.7:g.134695586C>A Codon: GGC/GTC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695586C>A Locations: - p.Gly415Val (Ensembl:ENSMUST00000100857) - c.1244G>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs30557046 | 425 | Y>C | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.32) Somatic: No Accession: NC_000072.7:g.134695556T>C Codon: TAC/TGC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695556T>C Locations: - p.Tyr425Cys (Ensembl:ENSMUST00000100857) - c.1274A>G (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388843659 | 446 | V>E | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.06) Somatic: No Accession: NC_000072.7:g.134695493A>T Codon: GTA/GAA Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695493A>T Locations: - p.Val446Glu (Ensembl:ENSMUST00000100857) - c.1337T>A (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs233007864 | 465 | Q>P | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.2) Somatic: No Accession: NC_000072.7:g.134695436T>G Codon: CAG/CCG Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695436T>G Locations: - p.Gln465Pro (Ensembl:ENSMUST00000100857) - c.1394A>C (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388868771 | 470 | R>M | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.19) Somatic: No Accession: NC_000072.7:g.134695421C>A Codon: AGG/ATG Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695421C>A Locations: - p.Arg470Met (Ensembl:ENSMUST00000100857) - c.1409G>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs217462491 | 474 | S>N | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.14) Somatic: No Accession: NC_000072.7:g.134695409C>T Codon: AGC/AAC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695409C>T Locations: - p.Ser474Asn (Ensembl:ENSMUST00000100857) - c.1421G>A (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs246872211 | 476 | V>L | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.4) Somatic: No Accession: NC_000072.7:g.134695404C>G Codon: GTC/CTC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695404C>G Locations: - p.Val476Leu (Ensembl:ENSMUST00000100857) - c.1426G>C (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388872782 | 521 | Q>* | EVA | ||||
Consequence: stop gained Somatic: No Accession: NC_000072.7:g.134695269G>A Codon: CAA/TAA Consequence type: stop gained Cytogenetic band: 6q Genomic location: NC_000072.7:g.134695269G>A Locations: - p.Gln521Ter (Ensembl:ENSMUST00000100857) - c.1561C>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388843627 | 635 | N>T | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.58) Somatic: No Accession: NC_000072.7:g.134694926T>G Codon: AAC/ACC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134694926T>G Locations: - p.Asn635Thr (Ensembl:ENSMUST00000100857) - c.1904A>C (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: | |||||||
rs3388856260 | 652 | G>C | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000072.7:g.134694876C>A Codon: GGC/TGC Consequence type: missense Cytogenetic band: 6q Genomic location: NC_000072.7:g.134694876C>A Locations: - p.Gly652Cys (Ensembl:ENSMUST00000100857) - c.1954G>T (Ensembl:ENSMUST00000100857) Source type: large scale study Cross-references: |