In transgenic mice lipid droplets accumulation induced by retinal pigment cells (RPCs)-specific expression of human FATP1 was non-toxic and promoted mitochondrial energy metabolism in RPCs and non-autonomously in photoreceptor cells.
Several proteins that are expressed in the epidermis have been proposed to facilitate the uptake of long-chain fatty acids (LCFA) in mammalian cells CD36 fatty acid binding protein and FATP. (review)
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