Q6P6B1 · ERIC5_HUMAN
- ProteinGlutamate-rich protein 5
- GeneERICH5
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids374 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamate-rich protein 5
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ6P6B1
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_033176 | 59 | in dbSNP:rs7833473 | |||
Sequence: R → H | ||||||
Natural variant | VAR_033177 | 244 | in dbSNP:rs35368005 | |||
Sequence: Q → P | ||||||
Natural variant | VAR_033178 | 287 | in dbSNP:rs11994440 | |||
Sequence: H → R |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 446 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain, modified residue (large scale data), modified residue.
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Chain | PRO_0000294433 | 1-374 | UniProt | Glutamate-rich protein 5 | |||
Sequence: MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRNIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAAT | |||||||
Modified residue (large scale data) | 142 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue | 169 | UniProt | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 169 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 354 | PRIDE | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q6P6B1 | CFTR P13569 | 4 | EBI-11343491, EBI-349854 | |
BINARY | Q6P6B1 | KEAP1 Q14145 | 3 | EBI-11343491, EBI-751001 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-34 | Polar residues | ||||
Sequence: MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESES | ||||||
Region | 1-168 | Disordered | ||||
Sequence: MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKD | ||||||
Compositional bias | 124-138 | Basic and acidic residues | ||||
Sequence: APAAEGKKKDAGAGT | ||||||
Region | 241-299 | Disordered | ||||
Sequence: EEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQI | ||||||
Compositional bias | 328-367 | Basic and acidic residues | ||||
Sequence: HTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEV | ||||||
Region | 328-374 | Disordered | ||||
Sequence: HTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAAT |
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q6P6B1-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length374
- Mass (Da)39,936
- Last updated2004-07-05 v1
- Checksum78FEE6D3CEF9011A
Q6P6B1-2
- Name2
- Differences from canonical
- 20-337: Missing
Features
Showing features for compositional bias, alternative sequence, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-34 | Polar residues | ||||
Sequence: MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESES | ||||||
Alternative sequence | VSP_046650 | 20-337 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 124-138 | Basic and acidic residues | ||||
Sequence: APAAEGKKKDAGAGT | ||||||
Sequence conflict | 326 | in Ref. 1; BAC04880 | ||||
Sequence: N → S | ||||||
Compositional bias | 328-367 | Basic and acidic residues | ||||
Sequence: HTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEV |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK096872 EMBL· GenBank· DDBJ | BAC04880.1 EMBL· GenBank· DDBJ | mRNA | ||
AP003352 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AP003439 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CH471060 EMBL· GenBank· DDBJ | EAW91772.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC062359 EMBL· GenBank· DDBJ | AAH62359.1 EMBL· GenBank· DDBJ | mRNA |