Q6P572 · Q6P572_MOUSE

  • Protein
    Myotubularin-related protein 2
  • Gene
    Mtmr2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site258-261substrate
Binding site283-284substrate
Active site345Phosphocysteine intermediate
Binding site345-351substrate

GO annotations

AspectTerm
Cellular Componentearly endosome membrane
Molecular Functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Molecular Functionphosphatidylinositol-3-phosphate phosphatase activity
Biological Processlipid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Myotubularin-related protein 2
  • EC number
  • Alternative names
    • Phosphatidylinositol-3,5-bisphosphate 3-phosphatase
    • Phosphatidylinositol-3-phosphate phosphatase

Gene names

    • Name
      Mtmr2

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • C57BL/6
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q6P572

Proteomes

Organism-specific databases

Subcellular Location

Cytoplasm
Early endosome membrane
; Peripheral membrane protein
Endosome membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain133-508Myotubularin phosphatase
Domain314-361Tyrosine specific protein phosphatases
Region542-571Disordered
Compositional bias546-571Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    571
  • Mass (Da)
    65,768
  • Last updated
    2004-07-05 v1
  • Checksum
    3A0872B069D5927A
MEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTSYRLYFKSMERDPPFVLDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHSRYKELLAKRAELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9Z2D1MTMR2_MOUSEMtmr2643
F6T2Q0F6T2Q0_MOUSEMtmr267
B8JJF3B8JJF3_MOUSEMtmr2105
B8JJF6B8JJF6_MOUSEMtmr282

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias546-571Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC063050
EMBL· GenBank· DDBJ
AAH63050.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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