Q6NYJ7 · Q6NYJ7_DANRE

Function

Catalytic activity

  • Hydrolysis of proteins and small molecule substrates at -Asn-|-Xaa- bonds.
    EC:3.4.22.34 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

143850100150200250300350400
TypeIDPosition(s)Description
Active site150
Active site191Nucleophile

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentvacuole
Molecular Functioncysteine-type endopeptidase activity
Biological Processaxon regeneration
Biological Processproteolysis involved in protein catabolic process
Biological Processtissue regeneration
Biological Processvacuolar protein processing

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Legumain
  • EC number
  • Alternative names
    • Protease, cysteine 1

Gene names

    • Name
      lgmn
    • Synonyms
      cb173
      , cb460
      , sb:cb173
      , wu:fa98g05
      , wu:fj92g08
      , zgc:76953

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q6NYJ7

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-21
ChainPRO_503503603322-438Legumain

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain339-434Legumain prodomain

Sequence similarities

Belongs to the peptidase C13 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    438
  • Mass (Da)
    49,192
  • Last updated
    2004-07-05 v1
  • Checksum
    C6261245030222B4
MSPKTVAVLGLALSLGLVVSGFPAEQPENGKHWVVIVAGSNGWYNYRHQADVCHAYQIVHKNGIPDEQIVVMMYDDLAESPDNPTKGVVINRPNGSDVYKGVLKDYIGDDVTPENFLAVLKGDAASVKGGSGKVLKSGPNDHVFVYFTDHGAPGLLAFPNDDLHVDDLMDTIKYMHSNNKYKKMVFYVEACESGSMMKPLPVDINVYATTAANPDESSYACYYDEARDTYLGDWYSVNWMEDSDVEDLSKETLAKQFKIVKAKTNTSHVMQYGNKTLSHMKVMAFQGSSKGLDKAVEPVSLPVIAEHDLMSSPDVPLAILKRKLQKTNDVDAVVGYLNEIHAHLQVRELLGNTMRKIVEHVVQDKEEVQDYLDGRSDLTQYNCYKTAVRHYKKHCFNWHEQKFEYALRHLYALVNLCEGGYQAHRITAAMDDVCYFRD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC066568
EMBL· GenBank· DDBJ
AAH66568.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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