Q6NXZ0 · Q6NXZ0_MOUSE

  • Protein
    Dipeptidyl peptidase 3
  • Gene
    Dpp3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

  • Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.
    EC:3.4.14.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

1738100200300400500600700
Type
IDPosition(s)Description
Binding site450Zn2+ (UniProtKB | ChEBI); catalytic
Active site451
Binding site455Zn2+ (UniProtKB | ChEBI); catalytic
Binding site508Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionaminopeptidase activity
Molecular Functiondipeptidyl-peptidase activity
Molecular Functionmetal ion binding
Molecular Functionmetalloexopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Dipeptidyl peptidase 3
  • EC number
  • Alternative names
    • Dipeptidyl aminopeptidase III
    • Dipeptidyl peptidase III

Gene names

    • Name
      Dpp3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q6NXZ0

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Family & Domains

Sequence similarities

Belongs to the peptidase M49 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    738
  • Mass (Da)
    82,955
  • Last updated
    2004-07-05 v1
  • MD5 Checksum
    4885266118BCA33E1DB11E2CAD638AAB
MADTQYILPNDIGVSSLNCREAFRLLSPTERLYAHHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKDKLGRVILGSKAAQQRPEEVRDLWQTCGDLMFSLEPRLRHLGLGKEGVTTYFSGDCTMEDAKLAQDFLDSQNLSAYNTRLFKVVDQEGKSHYEVRLASVLNTDPALDSELTSKLKRYEFQGNHFQVTRGDYAPILQKVVEHLEKAKAYAANSHQEQMLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFERLVASAEQLLKELPWPLAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYAAKREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDKETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLNPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAANWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVRLDRSKIRSVGRPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSEVQLVEYEASAAGLIRSFCERFPEDGPELEEVLIQLAAADARFWRNQAQEAPPGQA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC066817
EMBL· GenBank· DDBJ
AAH66817.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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