Q6NSN9 · Q6NSN9_DANRE
- ProteinApoptosis-stimulating of p53 protein 2
- Genetp53bp2a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1060 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | p53 binding | |
Biological Process | chordate embryonic development | |
Biological Process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | |
Biological Process | regulation of apoptotic process | |
Biological Process | signal transduction |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ6NSN9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, coiled coil, compositional bias, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 23-86 | Ras-associating | ||||
Sequence: TAETVCADVLQLCREPGENSSCYLSEVWRGSERVVGENEKMMDLLLQWGQQRPEVRFFLRHGRA | ||||||
Region | 84-116 | Disordered | ||||
Sequence: GRAASQPSDSRTQKRNGVKKPADRRLENGVNGP | ||||||
Coiled coil | 122-235 | |||||
Sequence: LAELQEMASRQQRQIDSQQQLLSTKEQRLRYLQQQEQRQAQSSSEQKKLLQLRETLEQQEAQLKMVRALKGQVEQKRLSNGKLVEQVEQMNNLLHQKQKELVVAVAKVEELSKQ | ||||||
Coiled coil | 268-298 | |||||
Sequence: KNLNVEQNAKLQQQRENLNKRNQEVANMDKR | ||||||
Region | 318-337 | Disordered | ||||
Sequence: NLPLPPDGQAPPQTPGSRVA | ||||||
Compositional bias | 401-423 | Polar residues | ||||
Sequence: KSGNNHVTSSLPRMVSQASKSQD | ||||||
Region | 401-436 | Disordered | ||||
Sequence: KSGNNHVTSSLPRMVSQASKSQDNTDVQKRDPRVRP | ||||||
Region | 472-547 | Disordered | ||||
Sequence: KVPPPVPSKPKQANFPSGGLMGLGKNTGTYPGKSASPQPPAGPQTGTLPSKLEAPPAATVHPFSPDPPGAKDTGGQ | ||||||
Region | 566-585 | Disordered | ||||
Sequence: QQPSSGKATQQSIQGALSRA | ||||||
Region | 597-657 | Disordered | ||||
Sequence: GKPVTSAGQPSQTPHPENPYLDPPSVSETLTDHSPAEPISETPETERIPRPLSPTKLLPFI | ||||||
Compositional bias | 620-634 | Polar residues | ||||
Sequence: PSVSETLTDHSPAEP | ||||||
Region | 713-845 | Disordered | ||||
Sequence: METVSPPGEEEKETLAKPQGYDAETPEVPEETLPEFPIAPEVEAEDVPPPPPPHPAPKIDASIIIPPPQPESPPPPPPPDSFMEDFPPYPPPPYPSSAEQDNPDDTFNMKPPEVTGQVPFPPGKRTNLRKSGS | ||||||
Compositional bias | 755-810 | Pro residues | ||||
Sequence: EAEDVPPPPPPHPAPKIDASIIIPPPQPESPPPPPPPDSFMEDFPPYPPPPYPSSA | ||||||
Repeat | 890-922 | ANK | ||||
Sequence: EGITALHNAVCAGHTEIVKFLVQYGVNVNAADS | ||||||
Repeat | 923-955 | ANK | ||||
Sequence: DGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY | ||||||
Domain | 989-1051 | SH3 | ||||
Sequence: MNRGVVYGLWDYEAAQEDECSFREGDCMSVIRREDELETDWWWVCCGGAEGYVPRNLLGLYPR |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,060
- Mass (Da)117,606
- Last updated2004-07-05 v1
- Checksum1B1D193641F0E60B
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F1R419 | F1R419_DANRE | tp53bp2a | 1060 | ||
A0A8M2B2J1 | A0A8M2B2J1_DANRE | tp53bp2a | 1055 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 401-423 | Polar residues | ||||
Sequence: KSGNNHVTSSLPRMVSQASKSQD | ||||||
Compositional bias | 620-634 | Polar residues | ||||
Sequence: PSVSETLTDHSPAEP | ||||||
Compositional bias | 755-810 | Pro residues | ||||
Sequence: EAEDVPPPPPPHPAPKIDASIIIPPPQPESPPPPPPPDSFMEDFPPYPPPPYPSSA |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC070005 EMBL· GenBank· DDBJ | AAH70005.1 EMBL· GenBank· DDBJ | mRNA |