Q6NP60 · MOX12_DROME
- ProteinMOXD1 homolog 2
- Geneolf413
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids760 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | extracellular space | |
Cellular Component | secretory granule membrane | |
Molecular Function | copper ion binding | |
Molecular Function | dopamine beta-monooxygenase activity | |
Biological Process | dopamine catabolic process | |
Biological Process | norepinephrine biosynthetic process | |
Biological Process | octopamine biosynthetic process |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMOXD1 homolog 2
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ6NP60
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 47-67 | Helical | ||||
Sequence: CFISCHTFNLFLLLLLLASGV | ||||||
Transmembrane | 740-760 | Helical | ||||
Sequence: FISCLLWLGASSWWLLLMLRT |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000305222 | 1-760 | MOXD1 homolog 2 | |||
Sequence: MAHPRKAVATPATLQLGPPAQTAQSPAATLRHSRTASSSRRLSLIRCFISCHTFNLFLLLLLLASGVRAASKLATRSNKTSGSSTASGVGAGTAATSAAAAAASGTPIWDHAIDLNDDFRILWQIINQDITFEIQARTLGYVGFGFSPDGNLAGADMAIGWVDKGQTYFQDRHVTRNGDPEPVVDPSQDYMLMLGYENATHTVLRFRRKLDTCDPSHDIAITNDTMRLLYMYHAQDPPHGSVRPGTLPDPARAFRPYRPMVLMQRAQLPMPSPTHDERVRVLELRNEDVELPAGDLPLFWCKMFKLEDINRKHHLIRYEPIYDSSSSVHYLQHITLHECQGAHAELEEMAREQGRPCLGARSIPLACNAIVASWSRGSEGFTYPHEAGYPIESRQAKYYLMETHYNNLKPDFAQLHARQMADNSGLKIYFTHVLRPNDAGTLSIGMDPNWRHIIPPGQKRVVSEGQCIEDCTGYAFPQQGINIFAVMMRTHQIGKEVKLRQIRQTEELPPIAHDSNIDVAYQDFRRLPQSVHSMPGDRLIAECIYDSSSRKAITLGGLTMKEESCTVLTLYYPRQKKLTTCHSLPSLPTVLHSLGIEQLATDSNPVLISSPPELAGMTLEARLISYDWENQFGEFQEATRKGSFKPICWGAKNHVVPGSEFLEGYSINVTKTYKKHRRCKPKRPLAPPTERTAPPPASDLSELPVLHELDNNNIIEGAARSSRSSATDVHSLSRGSGRHFISCLLWLGASSWWLLLMLRT | ||||||
Glycosylation | 78 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 198 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 223 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 339↔367 | |||||
Sequence: CQGAHAELEEMAREQGRPCLGARSIPLAC | ||||||
Disulfide bond | 467↔581 | |||||
Sequence: CIEDCTGYAFPQQGINIFAVMMRTHQIGKEVKLRQIRQTEELPPIAHDSNIDVAYQDFRRLPQSVHSMPGDRLIAECIYDSSSRKAITLGGLTMKEESCTVLTLYYPRQKKLTTC | ||||||
Disulfide bond | 543↔565 | |||||
Sequence: CIYDSSSRKAITLGGLTMKEESC | ||||||
Glycosylation | 668 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-34 | Disordered | ||||
Sequence: MAHPRKAVATPATLQLGPPAQTAQSPAATLRHSR | ||||||
Compositional bias | 15-34 | Polar residues | ||||
Sequence: QLGPPAQTAQSPAATLRHSR | ||||||
Domain | 117-233 | DOMON | ||||
Sequence: DDFRILWQIINQDITFEIQARTLGYVGFGFSPDGNLAGADMAIGWVDKGQTYFQDRHVTRNGDPEPVVDPSQDYMLMLGYENATHTVLRFRRKLDTCDPSHDIAITNDTMRLLYMYH | ||||||
Region | 678-701 | Disordered | ||||
Sequence: RCKPKRPLAPPTERTAPPPASDLS |
Sequence similarities
Belongs to the copper type II ascorbate-dependent monooxygenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length760
- Mass (Da)84,741
- Last updated2004-07-05 v1
- ChecksumCA350B5E07CBED04
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
M9PDA4 | M9PDA4_DROME | olf413 | 760 |
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 15-34 | Polar residues | ||||
Sequence: QLGPPAQTAQSPAATLRHSR | ||||||
Sequence conflict | 598 | in Ref. 1; AAG16682 | ||||
Sequence: Q → H | ||||||
Sequence conflict | 656-657 | in Ref. 1; AAG16682 | ||||
Sequence: VP → LLFITPQ |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF255741 EMBL· GenBank· DDBJ | AAG16682.1 EMBL· GenBank· DDBJ | mRNA | Frameshift | |
AE014296 EMBL· GenBank· DDBJ | AAF51810.4 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT011070 EMBL· GenBank· DDBJ | AAR31141.1 EMBL· GenBank· DDBJ | mRNA |