Q6N2N5 · SAHH_RHOPA

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site58substrate
Binding site133substrate
Binding site195substrate
Binding site196-198NAD+ (UniProtKB | ChEBI)
Binding site225substrate
Binding site229substrate
Binding site230NAD+ (UniProtKB | ChEBI)
Binding site259-264NAD+ (UniProtKB | ChEBI)
Binding site282NAD+ (UniProtKB | ChEBI)
Binding site317NAD+ (UniProtKB | ChEBI)
Binding site338-340NAD+ (UniProtKB | ChEBI)
Binding site383NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • Ordered locus names
      RPA4015

Organism names

Accessions

  • Primary accession
    Q6N2N5

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001169841-469Adenosylhomocysteinase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    469
  • Mass (Da)
    51,699
  • Last updated
    2004-07-05 v1
  • MD5 Checksum
    705F37287400BBBC2F129DE32117AC5F
MTAKFTDYIVKDIGLAEFGRKEISLAETEMPGLMATREEYGPKQPLKGAKIAGSLHMTIQTAVLIETLVALGAEVRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLKDYWDYTAKLFDWSDGGTPNMILDDGGDATMFVHQGLRAENGDTMFLDQHNSEEEEIFFALIKRILKEKPKGYFATLAKNIKGVSEETTTGVHRLYDMEKAGKLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYQVVTMEDAAPIADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQVATLKNMKWDNIKPQVDEITFPDGKRMILLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFQNQGKYEKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKVEGPFKADHYRY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX572606
EMBL· GenBank· DDBJ
CAE29456.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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