Q6MS92 · ATPA_MYCMS

Function

function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

Catalytic activity

Features

Showing features for binding site, site.

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TypeIDPosition(s)Description
Binding site169-176ATP (UniProtKB | ChEBI)
Site362Required for activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentproton-transporting ATP synthase complex, catalytic core F(1)
Molecular FunctionATP binding
Molecular Functionproton-transporting ATP synthase activity, rotational mechanism
Molecular Functionproton-transporting ATPase activity, rotational mechanism

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP synthase subunit alpha
  • EC number
  • Alternative names
    • ATP synthase F1 sector subunit alpha
    • F-ATPase subunit alpha

Gene names

    • Name
      atpA
    • Ordered locus names
      MSC_0887

Organism names

Accessions

  • Primary accession
    Q6MS92

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002382951-525ATP synthase subunit alpha

Interaction

Subunit

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    525
  • Mass (Da)
    58,203
  • Last updated
    2004-07-05 v1
  • Checksum
    CBAD3A565D03024A
MSFNIKEISEMIEEQIRNYNKEIVQTEQGTVVSVGDGIALIYGLDNAIMGEFLKFPNNVYGMVLNLEESAVGAIILGDETLIREGDIVKRTNKVVETPVGDALLGRVINALSKPIDNLGPINFTKTRPIERVATSVMARRSVSQPLETGILAIDSAIPIGKGQRELIIGDRQTGKTAIAIDAIINQKNKNVKCIYVAIGQKDSTIVQVVEKLKKYGAMEYTVVVNAGASQPAPLQYLSPYVGVTIAEEWMENGNDVLIIYDDLSKHAVSYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAARVNENYGGGSITALPIIETQAGDISAYIPTNVISITDGQIFLSSELFNQGVRPAVDIGSSVSRVGSAAQIKSIKQVSGTLKLELAQYYELELFAKFGSDLDEATKATLDQGAKIIQMLIQKQHNPLEQVDQAILLLTIKSHLIKWLPVESIYNFKHEILSHFKNDKHAFELRKKLDEQKTFDDQLQQQILKEAQKVVLKITKNINEYKPGTFGNISEYQNLGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX293980
EMBL· GenBank· DDBJ
CAE77498.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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