Q6MD64 · IF2_PARUW

Function

function

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

Features

Showing features for binding site.

1920100200300400500600700800900
TypeIDPosition(s)Description
Binding site427-434GTP (UniProtKB | ChEBI)
Binding site473-477GTP (UniProtKB | ChEBI)
Binding site527-530GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functiontranslation initiation factor activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Translation initiation factor IF-2

Gene names

    • Name
      infB
    • Ordered locus names
      pc0761

Organism names

Accessions

  • Primary accession
    Q6MD64

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002282211-920Translation initiation factor IF-2

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region27-112Disordered
Compositional bias48-67Basic and acidic residues
Compositional bias80-112Basic and acidic residues
Region143-325Disordered
Compositional bias202-219Basic and acidic residues
Compositional bias234-320Basic and acidic residues
Domain418-585tr-type G
Region427-434G1
Region452-456G2
Region473-476G3
Region527-530G4
Region563-565G5

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    920
  • Mass (Da)
    101,783
  • Last updated
    2004-07-05 v1
  • Checksum
    67B581DDB0A94631
MAKNLKLNIKNAQIAEAINLSGLKSKLAKKKEEESTQKSSAAKSTSKTTKTEVEELPKEEAPRIRARSKSAFAEAPADQSSKEITEEIKTSQDEESISREAAKVIEEKSRMKTSAEIRQEIFGEELSQAPSKDSSQELEFAEKIKTNETKPTTFIEPTIASPAPAEPKSLVEDKTSITHVYQNQKRDIPIRESLPPQEKLGPTGKHMRDFIKPKPQPERVSRPLEANNSNQKEVSEANKEKLDKNKIKPKSKGFEEPKVLTADDDARKGLKSPKFKEFKDIKPARKPETRQFDARDRQGLRTSDEDQHWRKKKNKQRQNIQEDTTIRPTSLKVRLPISIKDLASEMKLKASQLVGKLFLQGIVVTLNDLLEDETTAQLLGQEFGCEITIDTAEEKRIQITDKSIREELQQSPTDQLQLRPPVVAFMGHVDHGKTSLIDAIRKSNRAAGEAGAITQHIGAFRCHTTVGDIAILDTPGHEAFSAMRARGADVTDIVVLVVAGDEGLRQQSIEAIQHARAANVIIVVAINKCDKPNFNPDNVYRQLAEQNLLPEPWGGQTITVNCSAVTGEGIPELLEMLALQAEVLELRANPSMRARGTVLESEMHKGLGSVATILVQNGTLKRGDALVFGLLWGRVKTMHDEYGKELQEAGPSTPVEITGLSGLPEAGQEFIVVKNEKEAREIANVRSEGARQNTFMLQQKKKVSMENMLQQASATGKKMLNIVLRADVQGSLEALKVALLKIESDKADLNIIFNGVGEVSESDVQLAAASKAIVLGFHTQIESHAEALVKQLGVQVRLHNIIYHAIDDIKVLMAGLLEKIAQETEKGKAIVKATFKSSQAGIIAGCQVIEGSIHRNNYVRLKRGQEVIWKGTISSLKRVKEDVREVQKGIECGILLNNFTDILEGDIIEAYDITYISQEL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias48-67Basic and acidic residues
Compositional bias80-112Basic and acidic residues
Compositional bias202-219Basic and acidic residues
Compositional bias234-320Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX908798
EMBL· GenBank· DDBJ
CAF23485.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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