Q6L5H6 · P2C50_ORYSJ

Function

function

Protein phosphatase involved in abscisic acid (ABA) signaling. Together with PYL3 and SAPK10, may form an ABA signaling module involved in stress response.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium or manganese ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site118Mn2+ 1 (UniProtKB | ChEBI)
Binding site118Mn2+ 2 (UniProtKB | ChEBI)
Binding site119Mn2+ 1 (UniProtKB | ChEBI)
Binding site306Mn2+ 2 (UniProtKB | ChEBI)
Binding site368Mn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionmyosin phosphatase activity
Molecular Functionprotein serine/threonine phosphatase activity
Biological Processabscisic acid-activated signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein phosphatase 2C 50
  • EC number
  • Short names
    OsPP2C50
  • Alternative names
    • ABI1-like protein 3
      (OsABI-LIKE3
      ; OsABIL3
      )

Gene names

    • Name
      PP2C50
    • Synonyms
      ABIL3
    • ORF names
      OJ1741_B01.18
      , OSJNBa0052K01.2
    • Ordered locus names
      Os05g0537400
      , LOC_Os05g46040

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q6L5H6
  • Secondary accessions
    • Q0DGE0

Proteomes

Genome annotation databases

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis265Decreases binding affinity to PYL3 15-fold; when associated with M-267.
Mutagenesis265Abolishes interaction with PYR/PYL/RCAR abscisic acid intracellular receptors; when associated with K-267.
Mutagenesis267Abolishes interaction with PYR/PYL/RCAR abscisic acid intracellular receptors; when associated with K-265.
Mutagenesis267Decreases binding affinity to PYL3 15-fold; when associated with F-265.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003632971-387Protein phosphatase 2C 50

Proteomic databases

Expression

Induction

Induced by abscisic acid (ABA).

Interaction

Subunit

Interacts with PYL3, PYL5, PYL9 and PYL10. Binding to PYL3, PYL5, PYL9 and PYL10 is dependent on the presence of abscisic acid (ABA). Interacts with SAPK10.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain60-377PPM-type phosphatase
Motif264-268Modulates binding affinity to PYR/PYL/RCAR abscisic acid intracellular receptors

Sequence similarities

Belongs to the PP2C family.

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q6L5H6-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    387
  • Mass (Da)
    41,554
  • Last updated
    2004-07-05 v1
  • Checksum
    8DE5BAF0E1CCA2E6
MAAAAAAAAICGEDETAARVGCTGEWAGGIERVDLGERKEAVAAAGAGKRSVYLMDCAPVWGCASTRGRSAEMEDASAAVPRFADVPVRLLASRRDLDALGLDADALRLPAHLFGVFDGHGGAEVANYCRERIHVVLSEELKRLGKNLGEMGEVDMKEHWDDVFTKCFQRVDDEVSGRVTRVVNGGGEVRSEPVTAENVGSTAVVALVCSSHVVVANCGDSRIVLCRGKEPVALSIDHKPDRKDERARIEAQGGKVIQWNGYRVSGILAMSRSIGDRYLKPFVIPKPEVMVVPRAKDDDCLILASDGLWDVVSNEEACKVARRQILLWHKNNGAASPLSDEGEGSTDPAAQAAADYLMRLALKKGSEDNITVIVVDLKPRKKLKNIS

Q6L5H6-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Features

Showing features for alternative sequence.

TypeIDPosition(s)Description
Alternative sequenceVSP_036271276-296in isoform 2
Alternative sequenceVSP_036272297-387in isoform 2

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC097112
EMBL· GenBank· DDBJ
AAT39223.1
EMBL· GenBank· DDBJ
Genomic DNA
AC119291
EMBL· GenBank· DDBJ
AAV59393.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008211
EMBL· GenBank· DDBJ
BAF18083.2
EMBL· GenBank· DDBJ
Genomic DNA
AP014961
EMBL· GenBank· DDBJ
BAS95091.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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