Q6KZJ4 · RNZ_PICTO
- ProteinRibonuclease Z
- Genernz
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids309 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Catalytic activity
Cofactor
Note: Binds 2 Zn2+ ions.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 64 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 66 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Active site | 68 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 68 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: D | ||||||
Binding site | 69 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 141 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 209 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: D | ||||||
Binding site | 209 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: D | ||||||
Binding site | 267 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3'-tRNA processing endoribonuclease activity | |
Molecular Function | zinc ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease Z
- EC number
- Short namesRNase Z
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Candidatus Thermoplasmatota > Thermoplasmata > Thermoplasmatales > Picrophilaceae > Picrophilus
Accessions
- Primary accessionQ6KZJ4
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000155930 | 1-309 | Ribonuclease Z | |||
Sequence: MASTFKITFLGTGGSVPKPGRGLPAIAVQVDNIVNLFDCGEGTQKQFMKSGVSFMNVKNIFISHFHGDHFFGLPGLLSTFSFNGRIDDLNIFGPPGTIDEIKKVLSLIDFKITYNIKIAEMEENKKYDFDLFDVYAIKNDHTKYGYSYKLKEKDLIKINREKADSIGFPKNKLELLRNNGEYYYMGKRYSIWDVADGIKPGRSIVYSGDTRPFNDMLKFASNCDVLIHDSTMDASIENLANEYGHSTARQAAEIALKANVKRLFLFHYSSRYNDLNLLLNEAKSIFNDSYLSREMLEFNVDKKTELIKI |
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length309
- Mass (Da)35,185
- Last updated2004-07-05 v1
- ChecksumD829880E53A54B7E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE017261 EMBL· GenBank· DDBJ | AAT43858.1 EMBL· GenBank· DDBJ | Genomic DNA |