Q6IV20 · GLL11_CHICK

Function

function

Has bactericidal activity.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular FunctionCCR6 chemokine receptor binding
Biological Processdefense response to Gram-negative bacterium
Biological Processdefense response to Gram-positive bacterium
Biological Processinnate immune response in mucosa

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Gallinacin-11
  • Short names
    Gal-11
  • Alternative names
    • Beta-defensin 11
    • Vitelline membrane outer layer protein 2
    • Vitelline membrane outer layer protein II (VMO-II; VMOII)

Gene names

    • Name
      GAL11

Organism names

  • Taxonomic identifier
  • Strains
    • Guangxi Huang
    • Huiyang bearded
    • Qingyuan Ma
    • Taihe silkies
    • Xinghua
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus

Accessions

  • Primary accession
    Q6IV20
  • Secondary accessions
    • A0A1W6
    • Q09MT4
    • Q9PS49

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant35in strain: Huiyang bearded

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 7 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_000028857523-104Gallinacin-11
Disulfide bond30↔60
Disulfide bond37↔53
Disulfide bond43↔61

Keywords

Proteomic databases

Expression

Tissue specificity

Detected in outer membrane of the vitelline layer of the egg (at protein level). Expressed in the liver, gall bladder, kidney, testis, ovary and male and female reproductive tracts. Expressed in the ovarian stroma, but not in the ovarian follicles. No expression is detected in bone marrow.

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the beta-defensin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    104
  • Mass (Da)
    11,650
  • Last updated
    2004-07-05 v1
  • Checksum
    1D3E63B15D37F36A
MKLFSCLMALLLFLLQAVPGLGLPRDTSRCVGYHGYCIRSKVCPKPFAAFGTCSWRQKTCCVDTTSDFHTCQDKGGHCVSPKIRCLEEQLGLCPLKRWTCCKEI

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8V0Y4Q7A0A8V0Y4Q7_CHICKAvBD11136
A0A8V0Y9F9A0A8V0Y9F9_CHICKAvBD11111
A0A8V0Y9G4A0A8V0Y9G4_CHICKAvBD11179

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict31in Ref. 3; ABJ90336
Sequence conflict34in Ref. 3; ABJ90336
Sequence conflict94in Ref. 3; ABJ90336

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY621313
EMBL· GenBank· DDBJ
AAT45551.1
EMBL· GenBank· DDBJ
mRNA
AY621326
EMBL· GenBank· DDBJ
AAT48935.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ677642
EMBL· GenBank· DDBJ
ABG73376.1
EMBL· GenBank· DDBJ
mRNA
DQ858308
EMBL· GenBank· DDBJ
ABI48223.1
EMBL· GenBank· DDBJ
mRNA
DQ858321
EMBL· GenBank· DDBJ
ABI48237.1
EMBL· GenBank· DDBJ
mRNA
DQ858334
EMBL· GenBank· DDBJ
ABI48250.1
EMBL· GenBank· DDBJ
mRNA
DQ858348
EMBL· GenBank· DDBJ
ABI48264.1
EMBL· GenBank· DDBJ
mRNA
DQ997047
EMBL· GenBank· DDBJ
ABJ90336.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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