The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainC57BL/6JTissueEmbryoCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.Radzishevsky I., Odeh M., Bodner O., Zubedat S., Shaulov L., Litvak M., Esaki K., Yoshikawa T., Agranovich B.[...], Wolosker H.View abstractSourceMGI: 1270849PubMedEurope PMCProc Natl Acad Sci U S A 120:e2302780120-e2302780120 (2023)Mapped to98
Enhanced BMP signaling leads to enlarged nasal cartilage formation in mice.Yamaguchi H., Swaminathan S., Mishina Y., Komatsu Y.View abstractSourceMGI: 1270849PubMedEurope PMCBiochem Biophys Res Commun 678:173-178 (2023)Mapped to85
Unconventional myosin VI in the heart: Involvement in cardiac dysfunction progressing with age.Karatsai O., Lehka L., Wojton D., Grabowska A.I., Duda M.K., Lenartowski R., Redowicz M.J.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCBiochim Biophys Acta Mol Basis Dis 1869:166748-166748 (2023)Mapped to99+
LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway.Chang J.H., Chou C.H., Wu J.C., Liao K.M., Luo W.J., Hsu W.L., Chen X.R., Yu S.L., Pan S.H.[...], Su K.Y.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCCommun Biol 6:389-389 (2023)Mapped to68
Ring domains are essential for GATOR2-dependent mTORC1 activation.Jiang C., Dai X., He S., Zhou H., Fang L., Guo J., Liu S., Zhang T., Pan W.[...], Wei W.View abstractCategoriesFunction, InteractionSourceMGI: 1270849PubMedEurope PMCMol. Cell 83:74-89 (2023)Cited in10Mapped to43
Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.Li H., Li C., Zhai W., Zhang X., Li L., Wu B., Yu B., Zhang P., Li J.[...], Zhang L.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCCell Rep 41:111435-111435 (2022)Mapped to99+
The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring's Muscle Development and Energy Homeostasis.Ghnaimawi S., Zhang S., Baum J.I., Huang Y.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCFront Physiol 13:881624-881624 (2022)Mapped to99+
<i>Tsc1</i> Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum.Serra I., Stravs A., Osorio C., Oyaga M.R., Schonewille M., Tudorache C., Badura A.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCFront Mol Neurosci 15:831687-831687 (2022)Mapped to80
GATOR2 complex-mediated amino acid signaling regulates brain myelination.Yu Z., Yang Z., Ren G., Wang Y., Luo X., Zhu F., Yu S., Jia L., Chen M.[...], Xiao B.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 119:0-0 (2022)Cited in1Mapped to79
MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model.Tidyman W.E., Goodwin A.F., Maeda Y., Klein O.D., Rauen K.A.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCDis Model Mech 15:dmm049166-dmm049166 (2022)Mapped to74
TLR5 Supports Development of Placental Labyrinthine Zone in Mice.Yiu J.H.C., Cheung S.W.M., Cai J., Chan K.S., Chen J., Cheong L.Y., Chau H.T., Xu A., Li R.H.W., Woo C.W.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCFront Cell Dev Biol 9:711253-711253 (2021)Mapped to99+
A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.Tiu G.C., Kerr C.H., Forester C.M., Krishnarao P.S., Rosenblatt H.D., Raj N., Lantz T.C., Zhulyn O., Bowen M.E.[...], Barna M.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCDev Cell 56:2089-2102.e11 (2021)Mapped to99+
mTOR deletion in neural crest cells disrupts cardiac outflow tract remodeling and causes a spectrum of cardiac defects through the mTORC1 pathway.Nie X., Ricupero C.L., Jiao K., Yang P., Mao J.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1270849PubMedEurope PMCDev Biol 477:241-250 (2021)Mapped to99+
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization.Ramirez-Martinez A., Zhang Y., Chen K., Kim J., Cenik B.K., McAnally J.R., Cai C., Shelton J.M., Huang J.[...], Olson E.N.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCNat Commun 12:690-690 (2021)Mapped to52
Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions.Navas-Perez E., Vicente-Garcia C., Mirra S., Burguera D., Fernandez-Castillo N., Ferran J.L., Lopez-Mayorga M., Alaiz-Noya M., Suarez-Pereira I.[...], Garcia-Fernandez J.View abstractCategoriesExpressionSourceMGI: 1270849PubMedEurope PMCGenome Biol 21:267-267 (2020)Mapped to75
mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.Zamfirescu R.C., Day M.L., Morris M.B.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCAm J Physiol Cell Physiol 320:C30-C44 (2021)Mapped to57
mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics.Nie X., Zheng J., Cruciger M., Yang P., Mao J.J.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCDev Biol 467:77-87 (2020)Mapped to99+
Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.Wei G., Gao N., Chen J., Fan L., Zeng Z., Gao G., Li L., Fang G., Hu K.[...], Li D.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCDevelopment 147:dev185678-dev185678 (2020)Mapped to99+
Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation.Pan M., Yin Y., Wang X., Wang Q., Zhang L., Hu H., Wang C.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCAutophagy 17:1873-1888 (2021)Mapped to99+
Vessel-derived angiocrine IGF1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis.Marchant C., Anderson P., Schwarz Q., Wiszniak S.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCDevelopment 147:dev190488-dev190488 (2020)Mapped to70
Lin28-mediated temporal promotion of protein synthesis is crucial for neural progenitor cell maintenance and brain development in mice.Herrlinger S., Shao Q., Yang M., Chang Q., Liu Y., Pan X., Yin H., Xie L.W., Chen J.F.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCDevelopment 146:dev173765-dev173765 (2019)Mapped to79
New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to beta-adrenergic stimulation-induced cardiac fibrosis.Takahara S., Inoue S.I., Miyagawa-Tomita S., Matsuura K., Nakashima Y., Niihori T., Matsubara Y., Saiki Y., Aoki Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1270849PubMedEurope PMCEBioMedicine 42:43-53 (2019)Mapped to81
Pacer is a mediator of mTORC1 and GSK3-TIP60 signaling in regulation of autophagosome maturation and lipid metabolism.Cheng X., Ma X., Zhu Q., Song D., Ding X., Li L., Jiang X., Wang X., Tian R.[...], Sun Q.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCMol. Cell 73:1-15 (2019)Cited in8Mapped to47
Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis.Iezaki T., Horie T., Fukasawa K., Kitabatake M., Nakamura Y., Park G., Onishi Y., Ozaki K., Kanayama T.[...], Hinoi E.View abstractCategoriesFunctionSourceMGI: 1270849PubMedEurope PMCStem Cell Reports 11:228-241 (2018)Mapped to78