Q6IQ50 · Q6IQ50_HUMAN
- ProteinNOTCH2 protein
- GeneNOTCH2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1235 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | calcium ion binding | |
Biological Process | Notch signaling pathway |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ6IQ50
Disease & Variants
Organism-specific databases
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-25 | ||||
Chain | PRO_5004275902 | 26-1235 | |||
Disulfide bond | 53↔62 | ||||
Disulfide bond | 73↔90 | ||||
Disulfide bond | 92↔101 | ||||
Disulfide bond | 133↔142 | ||||
Disulfide bond | 170↔179 | ||||
Disulfide bond | 209↔218 | ||||
Disulfide bond | 248↔257 | ||||
Disulfide bond | 286↔295 | ||||
Disulfide bond | 326↔335 | ||||
Disulfide bond | 364↔373 | ||||
Disulfide bond | 384↔401 | ||||
Disulfide bond | 403↔412 | ||||
Disulfide bond | 444↔453 | ||||
Disulfide bond | 482↔491 | ||||
Disulfide bond | 520↔529 | ||||
Disulfide bond | 558↔567 | ||||
Disulfide bond | 574↔584 | ||||
Disulfide bond | 595↔604 | ||||
Disulfide bond | 633↔642 | ||||
Disulfide bond | 649↔659 | ||||
Disulfide bond | 670↔679 | ||||
Disulfide bond | 708↔717 | ||||
Disulfide bond | 724↔734 | ||||
Disulfide bond | 745↔754 | ||||
Disulfide bond | 783↔792 | ||||
Disulfide bond | 821↔830 | ||||
Disulfide bond | 842↔859 | ||||
Disulfide bond | 861↔870 | ||||
Disulfide bond | 899↔908 | ||||
Disulfide bond | 975↔984 | ||||
Disulfide bond | 1013↔1022 | ||||
Disulfide bond | 1051↔1060 | ||||
Disulfide bond | 1089↔1098 | ||||
Disulfide bond | 1137↔1146 | ||||
Disulfide bond | 1175↔1184 | ||||
Keywords
- PTM
Proteomic databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 24-63 | EGF-like | |||
Domain | 64-102 | EGF-like | |||
Domain | 105-143 | EGF-like | |||
Domain | 144-180 | EGF-like | |||
Domain | 182-219 | EGF-like | |||
Domain | 221-258 | EGF-like | |||
Domain | 260-296 | EGF-like | |||
Domain | 298-336 | EGF-like | |||
Domain | 338-374 | EGF-like | |||
Domain | 375-413 | EGF-like | |||
Domain | 415-454 | EGF-like | |||
Domain | 456-492 | EGF-like | |||
Domain | 494-530 | EGF-like | |||
Domain | 532-568 | EGF-like | |||
Domain | 570-605 | EGF-like | |||
Domain | 607-643 | EGF-like | |||
Domain | 645-680 | EGF-like | |||
Domain | 682-718 | EGF-like | |||
Domain | 720-755 | EGF-like | |||
Domain | 757-793 | EGF-like | |||
Domain | 795-831 | EGF-like | |||
Domain | 833-871 | EGF-like | |||
Domain | 873-909 | EGF-like | |||
Domain | 911-947 | EGF-like | |||
Domain | 949-985 | EGF-like | |||
Domain | 987-1023 | EGF-like | |||
Domain | 1025-1061 | EGF-like | |||
Domain | 1063-1099 | EGF-like | |||
Domain | 1112-1147 | EGF-like | |||
Domain | 1149-1185 | EGF-like | |||
Domain | 1187-1223 | EGF-like | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,235
- Mass (Da)132,112
- Last updated2005-08-30 v2
- MD5 ChecksumEED1C4CC95BBCC8DFB65C59E4F1F820C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC071562 EMBL· GenBank· DDBJ | AAH71562.2 EMBL· GenBank· DDBJ | mRNA |