Q6IEQ7 · WRK24_ORYSJ
- ProteinWRKY transcription factor WRKY24
- GeneWRKY24
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids555 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Transcription activator (PubMed:26025535).
Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535).
Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535).
Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535).
Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535).
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 214-278 | WRKY 1 | ||||
Sequence: SQRRSSDDGYNWRKYGQKQVKGSENPRSYYKCTFPNCPTKKKVERSLDGQITEIVYKGTHNHAKP | ||||||
DNA binding | 379-444 | WRKY 2 | ||||
Sequence: SDIDILDDGYRWRKYGQKVVKGNPNPRSYYKCTTAGCPVRKHVERASHDLRAVITTYEGKHNHDVP |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | sequence-specific DNA binding | |
Biological Process | abscisic acid-activated signaling pathway | |
Biological Process | gibberellic acid mediated signaling pathway | |
Biological Process | negative regulation of abscisic acid-activated signaling pathway | |
Biological Process | negative regulation of gibberellic acid mediated signaling pathway | |
Biological Process | positive regulation of DNA-templated transcription | |
Biological Process | response to abscisic acid | |
Biological Process | response to gibberellin |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameWRKY transcription factor WRKY24
- Short namesOsWRKY24
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionQ6IEQ7
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000436950 | 1-555 | WRKY transcription factor WRKY24 | |||
Sequence: MTTSSSGSVETSANSRLGTFSFASASFTDLLGGNAGAGGGGVSRYKAMTPPSLPLSPPPVSPSSFFNSPIGMNQADFLGSPVLLTSSIFPSPTTGAFASQHFDWRPEVAAAQSADQGGKDEQRNSYSDFSFQTAPASEEAVRTTTFQPPVPPAPLGDEAYRSQQQQQPWGYQQQPAGMDAGANAASFGAAPFQATSSEMAPQVQGGGGYSQPQSQRRSSDDGYNWRKYGQKQVKGSENPRSYYKCTFPNCPTKKKVERSLDGQITEIVYKGTHNHAKPQNTRRNSGSSAAQVLQSGGDMSEHSFGGMSGTAATPENSSASFGDDEIRVGSPRAGNGGGDEFDDDEPDSKRWRKDGDGEGISMAGNRTVREPRVVVQTMSDIDILDDGYRWRKYGQKVVKGNPNPRSYYKCTTAGCPVRKHVERASHDLRAVITTYEGKHNHDVPAARGSAALYRPAPPAAAATSSHPYLPNQPPPMSYQPTGPQPYALRPDGFGGQGPFGGVVGGSSFGGFSGFDDARGSYMSQHQQQQRQNDAMHASRAKEEPGDDMFFQNSLY |
Proteomic databases
Expression
Tissue specificity
Expressed in aleurone cells (PubMed:15618416).
Mostly expressed in aleurone layers and leaves, and, to a lower extent, in roots, panicles and embryos (PubMed:26025535).
Mostly expressed in aleurone layers and leaves, and, to a lower extent, in roots, panicles and embryos (PubMed:26025535).
Induction
Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048).
Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416).
Accumulates in response to jasmonic acid (MeJA) (By similarity).
Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416).
Accumulates in response to jasmonic acid (MeJA) (By similarity).
Developmental stage
In dry seeds, expressed in aleurone cells and embryos. Levels drop rapidly but transiently in the embryos of imbibed seeds.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 133-183 | Disordered | ||||
Sequence: TAPASEEAVRTTTFQPPVPPAPLGDEAYRSQQQQQPWGYQQQPAGMDAGAN | ||||||
Compositional bias | 159-173 | Polar residues | ||||
Sequence: AYRSQQQQQPWGYQQ | ||||||
Compositional bias | 197-219 | Polar residues | ||||
Sequence: SEMAPQVQGGGGYSQPQSQRRSS | ||||||
Region | 197-248 | Disordered | ||||
Sequence: SEMAPQVQGGGGYSQPQSQRRSSDDGYNWRKYGQKQVKGSENPRSYYKCTFP | ||||||
Motif | 253-259 | Nuclear localization signal | ||||
Sequence: KKKVERS | ||||||
Region | 270-365 | Disordered | ||||
Sequence: KGTHNHAKPQNTRRNSGSSAAQVLQSGGDMSEHSFGGMSGTAATPENSSASFGDDEIRVGSPRAGNGGGDEFDDDEPDSKRWRKDGDGEGISMAGN | ||||||
Compositional bias | 274-298 | Polar residues | ||||
Sequence: NHAKPQNTRRNSGSSAAQVLQSGGD | ||||||
Compositional bias | 306-320 | Polar residues | ||||
Sequence: GMSGTAATPENSSAS | ||||||
Compositional bias | 337-359 | Basic and acidic residues | ||||
Sequence: GGDEFDDDEPDSKRWRKDGDGEG | ||||||
Region | 466-555 | Transcription repression of gibberellic acid (GA)-induced promoters | ||||
Sequence: HPYLPNQPPPMSYQPTGPQPYALRPDGFGGQGPFGGVVGGSSFGGFSGFDDARGSYMSQHQQQQRQNDAMHASRAKEEPGDDMFFQNSLY | ||||||
Region | 514-555 | Disordered | ||||
Sequence: FDDARGSYMSQHQQQQRQNDAMHASRAKEEPGDDMFFQNSLY | ||||||
Compositional bias | 519-534 | Polar residues | ||||
Sequence: GSYMSQHQQQQRQNDA |
Domain
The WRKY domain is required to bind DNA.
Sequence similarities
Belongs to the WRKY group II-a family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q6IEQ7-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length555
- Mass (Da)59,306
- Last updated2004-07-05 v1
- ChecksumB1936C9DCB313733
Q6IEQ7-2
- Name2
- Differences from canonical
- 1-198: Missing
Features
Showing features for alternative sequence, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_058455 | 1-198 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 159-173 | Polar residues | ||||
Sequence: AYRSQQQQQPWGYQQ | ||||||
Compositional bias | 197-219 | Polar residues | ||||
Sequence: SEMAPQVQGGGGYSQPQSQRRSS | ||||||
Compositional bias | 274-298 | Polar residues | ||||
Sequence: NHAKPQNTRRNSGSSAAQVLQSGGD | ||||||
Compositional bias | 306-320 | Polar residues | ||||
Sequence: GMSGTAATPENSSAS | ||||||
Compositional bias | 337-359 | Basic and acidic residues | ||||
Sequence: GGDEFDDDEPDSKRWRKDGDGEG | ||||||
Compositional bias | 519-534 | Polar residues | ||||
Sequence: GSYMSQHQQQQRQNDA |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY341849 EMBL· GenBank· DDBJ | AAQ20908.1 EMBL· GenBank· DDBJ | mRNA | ||
AY870608 EMBL· GenBank· DDBJ | AAW63717.1 EMBL· GenBank· DDBJ | mRNA | ||
BK005027 EMBL· GenBank· DDBJ | DAA05089.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP003315 EMBL· GenBank· DDBJ | BAB61266.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP008207 EMBL· GenBank· DDBJ | BAF06589.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP014957 EMBL· GenBank· DDBJ | BAS75019.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CM000138 EMBL· GenBank· DDBJ | EAZ14002.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK107199 EMBL· GenBank· DDBJ | BAG97993.1 EMBL· GenBank· DDBJ | mRNA |