Q6H6D2 · HEM3_ORYSJ
- ProteinPorphobilinogen deaminase, chloroplastic
- GeneHEMC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids358 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Miscellaneous
The porphobilinogen subunits are added to the dipyrromethane group.
Catalytic activity
- 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH4+
Cofactor
Note: Binds 1 dipyrromethane group covalently.
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.
Porphyrin-containing compound metabolism; chlorophyll biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Cellular Component | cytoplasm | |
Molecular Function | hydroxymethylbilane synthase activity | |
Biological Process | chlorophyll biosynthetic process | |
Biological Process | chloroplast RNA modification | |
Biological Process | heme biosynthetic process | |
Biological Process | peptidyl-pyrromethane cofactor linkage | |
Biological Process | protoporphyrinogen IX biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePorphobilinogen deaminase, chloroplastic
- EC number
- Short namesPBG
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionQ6H6D2
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, modified residue, modified residue (large scale data).
Type | ID | Position(s) | Source | Description | ||
---|---|---|---|---|---|---|
Signal | 1-24 | UniProt | ||||
Chain | PRO_0000376066 | 25-358 | UniProt | Porphobilinogen deaminase, chloroplastic | ||
Modified residue | 290 | UniProt | S-(dipyrrolylmethanemethyl)cysteine | |||
Modified residue (large scale data) | 318 | PTMeXchange | Phosphoserine | |||
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence & Isoform
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
This entry describes 2 isoforms produced by Alternative splicing.
Q6H6D2-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length358
- Mass (Da)38,397
- Last updated2004-07-19 v1
- Checksum551C55AFC7AF3943
Q6H6D2-2
- Name2
- Differences from canonical
- 1-94: Missing
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0P0VFC8 | A0A0P0VFC8_ORYSJ | Os02g0168800 | 303 |
Features
Showing features for alternative sequence.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Alternative sequence | VSP_037401 | 1-94 | in isoform 2 | ||
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP005071 EMBL· GenBank· DDBJ | BAD25717.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP005071 EMBL· GenBank· DDBJ | BAD25718.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP008208 EMBL· GenBank· DDBJ | BAF07931.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP014958 EMBL· GenBank· DDBJ | BAS77179.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CM000139 EMBL· GenBank· DDBJ | EEE56391.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK060914 EMBL· GenBank· DDBJ | BAG87614.1 EMBL· GenBank· DDBJ | mRNA | ||
AK102265 EMBL· GenBank· DDBJ | BAG95470.1 EMBL· GenBank· DDBJ | mRNA |