Q6GXA9 · Q6GXA9_MOUSE
- ProteinMetalloproteinase inhibitor 1
- GeneTimp1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids100 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Publications for Q6GXA9
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the mouse uterus during the peri-implantation period.
- CategoriesSequences, Expression
- SourceMGI: 98752
Tissue inhibitor of metalloproteinases-2 is expressed in the interstitial matrix in adult mouse organs and during embryonic development.
- CategoriesSequences, Expression
- SourceMGI: 98752
Metalloproteinases regulate parietal endoderm differentiating and migrating in cultured mouse embryos.
- CategoriesFunction, Expression
- SourceMGI: 98752
Temporal expression of tissue inhibitors of metalloproteinases in mouse reproductive tissues during gestation.
- CategoriesSequences, Expression
- SourceMGI: 98752
Increased expression of tissue inhibitor of metalloproteinases (TIMP-I) and metallothionein in murine lungs after hyperoxic exposure.
- CategoriesSequences, Expression
- SourceMGI: 98752
Assessment of 72-kilodalton gelatinase and TIMP-1 gene expression in normal and sclerotic murine glomeruli.
- CategoriesSequences, Expression
- SourceMGI: 98752
gamma-Linolenic acid in maternal milk drives cardiac metabolic maturation.
- CategoriesExpression
- SourceMGI: 98752
TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer.
- CategoriesFunction, Expression
- SourceMGI: 98752
Infiltrating CCR2<sup>+</sup> monocytes and their progenies, fibrocytes, contribute to colon fibrosis by inhibiting collagen degradation through the production of TIMP-1.
- AnnotationInfiltrating CCR2(+) monocytes and their progenies fibrocytes contribute to colon fibrosis by inhibiting collagen degradation through the production of TIMP-1.
- CategoriesFunction, Expression
Tissue inhibitor of metalloproteinases 1 enhances rod survival in the rd1 mouse retina.
- CategoriesFunction, Expression
- SourceMGI: 98752
Periodontitis aggravates kidney damage in obese mice by MMP2 regulation.
- AnnotationIn obese mice periodontitis caused the downregulation of MMP2 and upregulation of TIMP1 and TGF-beta1 at transcriptional and translational levels
- CategoriesFunction, Expression
- SourceGeneRif: 21857
Role of Galectin-3 in the pathophysiology underlying allergic lung inflammation in a tissue inhibitor of metalloproteinases 1 knockout model of murine asthma.
- CategoriesFunction, Expression, Phenotypes & Variants
- SourceMGI: 98752
TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice.
- AnnotationTIMP-1 is upregulated in liver fibrosis and hepatocellular carcinoma potentially implying diagnostic relevance in the non-invasive assessment of liver fibrosis or in HCC detection6. However our study in TIMP-1-deficient mice did not confirm a functional role of TIMP-1 in the development of liver fibrosis or hepatocellular carcinoma.
- CategoriesFunction, Expression
The MMP-9/TIMP-1 System is Involved in Fluoride-Induced Reproductive Dysfunctions in Female Mice.
- AnnotationThese results show that MMP-9/TIMP-1 system disturbance and changes of histological structure in uteri tissue are involved in fluoride-induced reproductive dysfunctions.
- CategoriesExpression
- SourceGeneRif: 21857
Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion.
- AnnotationTIMP-1 was identified as a selectively upregulated component secreted from immature astrocytes from human pluripotent stem cells.
- CategoriesExpression
Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA.
- CategoriesSequences, Expression
- SourceMGI: 98752