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Q6G9W0 · HSLV_STAAS

Function

function

Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

Catalytic activity

  • ATP-dependent cleavage of peptide bonds with broad specificity.
    EC:3.4.25.2 (UniProtKB | ENZYME | Rhea)

Activity regulation

Allosterically activated by HslU binding.

Features

Showing features for active site, binding site.

118120406080100120140160180
Type
IDPosition(s)Description
Active site9
Binding site166Na+ (UniProtKB | ChEBI)
Binding site169Na+ (UniProtKB | ChEBI)
Binding site172Na+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentHslUV protease complex
Cellular Componentproteasome core complex
Molecular Functionmetal ion binding
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent protease subunit HslV
  • EC number

Gene names

    • Name
      hslV
    • Ordered locus names
      SAS1187

Organism names

Accessions

  • Primary accession
    Q6G9W0

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001481501-181ATP-dependent protease subunit HslV

Interaction

Subunit

A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.

Structure

Family & Domains

Sequence similarities

Belongs to the peptidase T1B family. HslV subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    181
  • Mass (Da)
    19,572
  • Last updated
    2004-07-19 v1
  • MD5 Checksum
    3641A46E214F3A488890AFE50344016F
MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX571857
EMBL· GenBank· DDBJ
CAG42964.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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