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Q6FRV2 · GSHR_CANGA

Function

function

Maintains high levels of reduced glutathione in the cytosol.

Miscellaneous

The active site is a redox-active disulfide bond.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site46-54FAD (UniProtKB | ChEBI)
Active site465Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentfungal biofilm matrix
Cellular Componentmitochondrion
Cellular Componentnucleus
Cellular Componentperoxisome
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionglutathione-disulfide reductase (NADPH) activity
Molecular FunctionNADP binding
Biological Processcell redox homeostasis
Biological Processcellular response to oxidative stress
Biological Processglutathione metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione reductase
  • EC number
  • Short names
    GR; GRase

Gene names

    • Name
      GLR1
    • Ordered locus names
      CAGL0H05665g

Organism names

Accessions

  • Primary accession
    Q6FRV2

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain, disulfide bond.

Type
IDPosition(s)Description
ChainPRO_00000679661-476Glutathione reductase
Disulfide bond54↔59Redox-active

Keywords

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    476
  • Mass (Da)
    52,499
  • Last updated
    2004-07-19 v1
  • MD5 Checksum
    8EE18D47B36EB95F83E54A467CC01A89
MIVKRLFRTMAPVAKHFDYLVIGGGSGGVASSRRAASYGAKTLLIEGKALGGTCVNVGCVPKKVMWYASDLATRLTHAHEYGLAQNVPLSKESITFNWPEFKKKRDAYIHRLNGIYENNLKKEGVEVVFGWAKFNKDGNVEVTKHDNTTEVYSADRILVATGGKPVYPEKVPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSDSHLVIRGKTVLRKFDEIIQNTVTDYYVEEGINVHKETNVDKVEKDEKTGKLSVHLTNGQVLEDVDELIWTMGRRSLLGIGLENVGVKLNDKEQIITDEYQNTNVPNIYSLGDVSGRVELTPVAIAAGRKLSNRLFGPEQYRNDKLDYTNVPSVVFSHPEAGSIGLTEDEAIKQYGKDNIKVYTSKFTAMYYAMLEHKSPTRYKIICEGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR380954
EMBL· GenBank· DDBJ
CAG59975.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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