Q6FI00 · Q6FI00_HUMAN

  • Protein
    G1/S-specific cyclin-D1
  • Gene
    CCND1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentbicellular tight junction
Cellular Componentcyclin D1-CDK4 complex
Cellular Componentcytoplasm
Cellular Componentnuclear membrane
Cellular Componentnucleoplasm
Molecular Functioncyclin-dependent protein serine/threonine kinase regulator activity
Molecular Functionprotein kinase activity
Molecular Functionprotein kinase binding
Biological Processcell division
Biological Processendoplasmic reticulum unfolded protein response
Biological Processfat cell differentiation
Biological ProcessG1/S transition of mitotic cell cycle
Biological Processlactation
Biological Processliver regeneration
Biological Processmammary gland alveolus development
Biological Processmammary gland epithelial cell proliferation
Biological Processnegative regulation of epithelial cell differentiation
Biological Processnegative regulation of neuron apoptotic process
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processneuron differentiation
Biological Processpositive regulation of mammary gland epithelial cell proliferation
Biological Processre-entry into mitotic cell cycle
Biological Processregulation of G1/S transition of mitotic cell cycle
Biological ProcessWnt signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    G1/S-specific cyclin-D1

Gene names

    • Name
      CCND1
    • ORF names
      hCG_2016647

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q6FI00

Organism-specific databases

Subcellular Location

Keywords

Disease & Variants

Organism-specific databases

PTM/Processing

Keywords

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain62-146Cyclin-like
Domain155-287Cyclin C-terminal
Region262-295Disordered

Sequence similarities

Belongs to the cyclin family. Cyclin D subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    295
  • Mass (Da)
    33,729
  • Last updated
    2005-05-10 v1
  • Checksum
    3CC00C9905F58D3A
MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BT019844
EMBL· GenBank· DDBJ
AAV38647.1
EMBL· GenBank· DDBJ
mRNA
AK313136
EMBL· GenBank· DDBJ
BAG35955.1
EMBL· GenBank· DDBJ
mRNA
CR536538
EMBL· GenBank· DDBJ
CAG38775.1
EMBL· GenBank· DDBJ
mRNA
CR542099
EMBL· GenBank· DDBJ
CAG46896.1
EMBL· GenBank· DDBJ
mRNA
CH471076
EMBL· GenBank· DDBJ
EAW74748.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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