Q6F4N6 · Q6F4N6_ORYSJ
- ProteinS-adenosylmethionine decarboxylase proenzyme
- GeneSAMDC1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids392 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- S-adenosyl-L-methionine + H+ = S-adenosyl 3-(methylsulfanyl)propylamine + CO2
Cofactor
Note: Binds 1 pyruvoyl group covalently per subunit.
Pathway
Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 19 | substrate | |||
Binding site | 79 | substrate | |||
Site | 79-80 | Cleavage (non-hydrolytic); by autolysis | |||
Active site | 80 | Schiff-base intermediate with substrate; via pyruvic acid | |||
Active site | 94 | Proton donor; for catalytic activity | |||
Binding site | 239 | substrate | |||
Active site | 245 | Proton acceptor; for processing activity | |||
Active site | 258 | Proton acceptor; for processing activity | |||
Binding site | 262 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | adenosylmethionine decarboxylase activity | |
Biological Process | spermidine biosynthetic process | |
Biological Process | spermine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameS-adenosylmethionine decarboxylase proenzyme
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionQ6F4N6
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_5013990484 | 1-79 | S-adenosylmethionine decarboxylase beta chain | ||
Modified residue | 80 | Pyruvic acid (Ser); by autocatalysis | |||
Chain | PRO_5013990485 | 80-392 | S-adenosylmethionine decarboxylase alpha chain | ||
Keywords
- PTM
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length392
- Mass (Da)42,718
- Last updated2004-08-16 v1
- Checksum0DF1F61522C38FE3
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB122089 EMBL· GenBank· DDBJ | BAD26704.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK067682 EMBL· GenBank· DDBJ | BAG90538.1 EMBL· GenBank· DDBJ | mRNA | ||
AK101535 EMBL· GenBank· DDBJ | BAG95110.1 EMBL· GenBank· DDBJ | mRNA | ||
AK102445 EMBL· GenBank· DDBJ | BAG95558.1 EMBL· GenBank· DDBJ | mRNA | ||
AP014965 EMBL· GenBank· DDBJ | BAT08153.1 EMBL· GenBank· DDBJ | Genomic DNA |