AMPD1 C34T Polymorphism (rs17602729) Is Not Associated with Post-Exercise Changes of Body Weight Body Composition and Biochemical Parameters in Caucasian Females.
The metabolic-chronotropic response is decreased in skeletal muscle MAD deficiency suggesting a biological mechanism by which AMPD1 gene exerts cardiac effect
T allele of AMPD1 gene C34T polymorphism may be correlated with LVEF LVEDD and SBP which plays a protective role in the cardiac functions and blood pressure in cardiovascular disease patients.
AMPD1 34C>T variant is associated with higher infection susceptibility to community acquired pneumonia but not to ventilator associated pneumonia in sepsis pateints
The present study demonstrated a positive effect of C34T AMPD1 gene polymorphism in aortic stiffness and in inflammatory status in a high risk population of CAD subjects.
In a study of a Spanish and 2 North African cohorts frequency of the AMPD1 C34T mutation was lower in Berbers compared with the Alpujarra cohort. The GDF8 K153R substitution showed little variability among the three cohorts.
There was a lower frequency of the AMPD1 exon 2 T34 allele in elite Polish power-oriented athletes. The data suggested that the C allele may help athletes to attain elite status in power-oriented sports.
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