Q6F1P8 · TRMB_MESFL
- ProteintRNA (guanine-N(7)-)-methyltransferase
- GenetrmB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids223 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.
Catalytic activity
- guanosine46 in tRNA + S-adenosyl-L-methionine = N7-methylguanosine46 in tRNA + S-adenosyl-L-homocysteine
Pathway
tRNA modification; N7-methylguanine-tRNA biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 45 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 70 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 125 | ||||
Binding site | 125 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 129 | substrate | |||
Binding site | 161 | substrate | |||
Binding site | 201-204 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | tRNA methyltransferase complex | |
Molecular Function | tRNA (guanine(46)-N7)-methyltransferase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA (guanine-N(7)-)-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mollicutes > Entomoplasmatales > Entomoplasmataceae > Mesoplasma
Accessions
- Primary accessionQ6F1P8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000171347 | 1-223 | tRNA (guanine-N7-)-methyltransferase | ||
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length223
- Mass (Da)26,158
- Last updated2004-08-16 v1
- MD5 Checksum512BB5052E4B9CA056771AF8EBA70F44
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE017263 EMBL· GenBank· DDBJ | AAT75575.1 EMBL· GenBank· DDBJ | Genomic DNA |