Q6F0Q9 · PYRH_MESFL
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids238 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- ATP + UMP = ADP + UDP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 11-14 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KLSG | ||||||
Binding site | 52 | UMP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 53 | ATP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 57 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 72 | UMP (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 134-141 | UMP (UniProtKB | ChEBI) | ||||
Sequence: TGFSYFTT | ||||||
Binding site | 162 | ATP (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 168 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 171 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mollicutes > Entomoplasmatales > Entomoplasmataceae > Mesoplasma
Accessions
- Primary accessionQ6F0Q9
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000323882 | 1-238 | Uridylate kinase | |||
Sequence: MKYKYSTVLLKLSGEALKSENEIYNKEKLEDIAKQIVELAKNGLKLGIVIGGGNIWRGKLGTDIDMPQINADYMGMLATVMNGLALESTIKRLGYDKVNVYSSLPIETVTDDYNFKRARLKMNEGYISIFVGGTGFSYFTTDTNSVIRAIEIGADAVLMAKNGVKGVYDSDPNLNPNAKFYKKLTHREIAENQLRVMDLTAATLAKDAKLPIEVFDMQGQNNIIKVMEGSLESTIIEE |
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length238
- Mass (Da)26,392
- Last updated2004-08-16 v1
- ChecksumDC6109400096E3A7
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE017263 EMBL· GenBank· DDBJ | AAT75914.1 EMBL· GenBank· DDBJ | Genomic DNA |