Q6EVA0 · Q6EVA0_BACIU

  • Protein
    Isopentenyl-diphosphate delta-isomerase
  • Gene
    idi-2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FMN (UniProtKB | Rhea| CHEBI:58210 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

NADPH (UniProtKB | Rhea| CHEBI:57783 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site6-7substrate
Binding site62-64FMN (UniProtKB | ChEBI)
Binding site93FMN (UniProtKB | ChEBI)
Binding site122FMN (UniProtKB | ChEBI)
Binding site152substrate
Binding site153Mg2+ (UniProtKB | ChEBI)
Binding site184FMN (UniProtKB | ChEBI)
Binding site214FMN (UniProtKB | ChEBI)
Binding site258-259FMN (UniProtKB | ChEBI)
Binding site280-281FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionFMN binding
Molecular Functionisopentenyl-diphosphate delta-isomerase activity
Molecular Functionmagnesium ion binding
Molecular FunctionNADPH binding
Molecular Functionoxidoreductase activity
Biological Processisoprenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isopentenyl-diphosphate delta-isomerase
  • EC number
  • Short names
    IPP isomerase
  • Alternative names
    • Isopentenyl diphosphate:dimethylallyl diphosphate isomerase
    • Isopentenyl pyrophosphate isomerase
    • Type 2 isopentenyl diphosphate isomerase
      (IDI-2
      )

Gene names

    • Name
      idi-2
    • Synonyms
      fni

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus

Accessions

  • Primary accession
    Q6EVA0

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer. Dimer of tetramers.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain166-324FMN-dependent dehydrogenase

Sequence similarities

Belongs to the IPP isomerase type 2 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    349
  • Mass (Da)
    37,221
  • Last updated
    2005-05-10 v1
  • Checksum
    3EA275B6EDEAB587
MTRAERKRQHINHALSIGQKRETGLDDITFVHVSLPDLALEQVDISTKIGELSSSSPIFINAMTGGGGKLTYEINKSLARAASQAGIPLAVGSQMSALKDPSERLSYEIVRKENPNGLIFANLGSEATAAQAKEAVEMIGANALQIHLNVIQEIVMPEGDRSFSGALKRIEQICSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYGGTNFSKIENLRRQRQISFFNSWGISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIALGASCTGMAGHFLKALTDSGEEGLLEEIQLILEELKLIMTVLGARTIADLQKAPLVIKGETHHWLTERGVNTSSYSVR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ781076
EMBL· GenBank· DDBJ
CAG77478.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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