AHR role in the GLK controlled IL-17A production and autoimmune responses.AhR interacts with ROR-gammat and transports ROR-gammat into the cell nucleus.
Signaling through beta-catenin activates basal CYP1A1 expression and augments CYP1A1 induction by aryl hydrocarbon receptor ligands through enhancement of the transactivation potential of the aryl hydrocarbon receptor.
the transcriptional activity of the CA9 promoter was significantly reduced by expression of CAAhR (constitutively active AhR) which activates transcription in a ligand-independent manner
Cyp1a1 induction by the AHR/ARNT is associated with modification of specific chromatin marks including hyperacetylation of histone H3K14 and H4K16 trimethylation of histone H3K4 and phosphorylation of H3S10.
carbaryl interacts with aryl hydrocarbon receptor but its peculiar structure imposes a substandard configuration on the aryl hydrocarbon receptor ligand-binding domain
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