Q6DHZ8 · Q6DHZ8_HUMAN
- ProteinActivity-dependent neuroprotector homeobox
- GeneADNP
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1102 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 773-815 | Homeobox | ||||
Sequence: KYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDC |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | metal ion binding | |
Biological Process | regulation of gene expression |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ6DHZ8
Subcellular Location
Disease & Variants
Organism-specific databases
PTM/Processing
Proteomic databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 354-443 | Disordered | ||||
Sequence: NAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSKPAAAATGPPPGNTSST | ||||||
Compositional bias | 356-443 | Polar residues | ||||
Sequence: PVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSKPAAAATGPPPGNTSST | ||||||
Domain | 512-540 | C2H2-type | ||||
Sequence: LSCPYCRSTFNDVEKMAAHMRMVHIDEEM | ||||||
Region | 691-712 | Disordered | ||||
Sequence: GKTQNGQDKTNAPSRLNQSPSL | ||||||
Compositional bias | 693-712 | Polar residues | ||||
Sequence: TQNGQDKTNAPSRLNQSPSL | ||||||
Domain | 771-814 | Homeobox | ||||
Sequence: LTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRD | ||||||
Compositional bias | 851-876 | Basic and acidic residues | ||||
Sequence: EKDSRVNASKTADKKLNLGKEDDSSS | ||||||
Region | 851-1030 | Disordered | ||||
Sequence: EKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKN | ||||||
Compositional bias | 903-967 | Basic and acidic residues | ||||
Sequence: ISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKD | ||||||
Compositional bias | 972-986 | Polar residues | ||||
Sequence: SESGPGSQQVSDFED | ||||||
Compositional bias | 1003-1023 | Basic and acidic residues | ||||
Sequence: SEDARSSKPAAKKKATMQGDR | ||||||
Compositional bias | 1043-1074 | Polar residues | ||||
Sequence: DQSQWKNASENDERLSNPQIEWQNSTIDSEDG | ||||||
Region | 1043-1102 | Disordered | ||||
Sequence: DQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDGVAEPMHGSLAGVKLSSQQA |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,102
- Mass (Da)123,447
- Last updated2004-08-16 v1
- Checksum2B6984E554DC766A
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 356-443 | Polar residues | ||||
Sequence: PVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSKPAAAATGPPPGNTSST | ||||||
Compositional bias | 693-712 | Polar residues | ||||
Sequence: TQNGQDKTNAPSRLNQSPSL | ||||||
Compositional bias | 851-876 | Basic and acidic residues | ||||
Sequence: EKDSRVNASKTADKKLNLGKEDDSSS | ||||||
Compositional bias | 903-967 | Basic and acidic residues | ||||
Sequence: ISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKD | ||||||
Compositional bias | 972-986 | Polar residues | ||||
Sequence: SESGPGSQQVSDFED | ||||||
Compositional bias | 1003-1023 | Basic and acidic residues | ||||
Sequence: SEDARSSKPAAKKKATMQGDR | ||||||
Compositional bias | 1043-1074 | Polar residues | ||||
Sequence: DQSQWKNASENDERLSNPQIEWQNSTIDSEDG |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC075794 EMBL· GenBank· DDBJ | AAH75794.1 EMBL· GenBank· DDBJ | mRNA |