Q6DC46 · Q6DC46_DANRE
- ProteinEctonucleoside triphosphate diphosphohydrolase 1
- Geneentpd1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids492 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Catalytic activity
- 2 H2O + ITP = 2 H+ + IMP + 2 phosphateThis reaction proceeds in the forward direction.
- 2 H2O + UTP = 2 H+ + 2 phosphate + UMPThis reaction proceeds in the forward direction.
- ADP + H2O = AMP + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + 2 H2O = AMP + 2 H+ + 2 phosphateThis reaction proceeds in the forward direction.
- ATP + H2O = ADP + H+ + phosphateThis reaction proceeds in the forward direction.
- CDP + H2O = CMP + H+ + phosphateThis reaction proceeds in the forward direction.
- CTP + 2 H2O = CMP + 2 H+ + 2 phosphateThis reaction proceeds in the forward direction.
- CTP + H2O = CDP + H+ + phosphateThis reaction proceeds in the forward direction.
- GDP + H2O = GMP + H+ + phosphateThis reaction proceeds in the forward direction.
- GTP + 2 H2O = GMP + 2 H+ + 2 phosphateThis reaction proceeds in the forward direction.
- H2O + IDP = H+ + IMP + phosphateThis reaction proceeds in the forward direction.
- H2O + ITP = H+ + IDP + phosphateThis reaction proceeds in the forward direction.
- H2O + UDP = H+ + phosphate + UMPThis reaction proceeds in the forward direction.
- H2O + UTP = H+ + phosphate + UDPThis reaction proceeds in the forward direction.
- a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + H+ + phosphateThis reaction proceeds in the forward direction.
- a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + H+ + phosphateThis reaction proceeds in the forward direction.
Cofactor
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | GDP phosphatase activity | |
Molecular Function | ribonucleoside triphosphate phosphatase activity | |
Molecular Function | UDP phosphatase activity | |
Biological Process | cellular response to methanol | |
Biological Process | nucleoside diphosphate catabolic process | |
Biological Process | response to copper ion | |
Biological Process | response to ethanol |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEctonucleoside triphosphate diphosphohydrolase 1
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ6DC46
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-34 | Helical | ||||
Sequence: PVVIFLMAVVAVGIVIMVSISVV | ||||||
Transmembrane | 458-480 | Helical | ||||
Sequence: YVTFMILFSLLILVLIIMAYIYF |
Keywords
- Cellular component
Interaction
Subunit
Homodimer; disulfide-linked.
Structure
Sequence
- Sequence statusComplete
- Length492
- Mass (Da)55,507
- Last updated2004-08-16 v1
- ChecksumB789AB6DFC6A032B
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
E7FG27 | E7FG27_DANRE | entpd1 | 496 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC078240 EMBL· GenBank· DDBJ | AAH78240.1 EMBL· GenBank· DDBJ | mRNA |