Q6CHE9 · EFM7_YARLI
- ProteinProtein N-terminal and lysine N-methyltransferase EFM7
- GeneEFM7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids273 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 65 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 92-94 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 114 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 161 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 183 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | N-terminal protein N-methyltransferase activity | |
Molecular Function | protein-lysine N-methyltransferase activity | |
Biological Process | N-terminal peptidyl-glycine methylation | |
Biological Process | peptidyl-lysine dimethylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein N-terminal and lysine N-methyltransferase EFM7
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Dipodascaceae > Yarrowia
Accessions
- Primary accessionQ6CHE9
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000096900 | 1-273 | Protein N-terminal and lysine N-methyltransferase EFM7 | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-32 | Disordered | |||
Compositional bias | 10-32 | Basic and acidic residues | |||
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length273
- Mass (Da)30,729
- Last updated2004-08-16 v1
- MD5 ChecksumDD28AD847D04FE01ACC47FC3E7701086
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 10-32 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR382127 EMBL· GenBank· DDBJ | CAG83839.1 EMBL· GenBank· DDBJ | Genomic DNA |