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Q6CHE9 · EFM7_YARLI

Function

function

S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

Features

Showing features for binding site.

127320406080100120140160180200220240260
TypeIDPosition(s)Description
Binding site65S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site92-94S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site114S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site161S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site183S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionN-terminal protein N-methyltransferase activity
Molecular Functionprotein-lysine N-methyltransferase activity
Biological ProcessN-terminal peptidyl-glycine methylation
Biological Processpeptidyl-lysine dimethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein N-terminal and lysine N-methyltransferase EFM7
  • EC number
  • Alternative names
    • Elongation factor methyltransferase 7

Gene names

    • Name
      EFM7
    • Synonyms
      NNT1
    • Ordered locus names
      YALI0A09636g

Organism names

Accessions

  • Primary accession
    Q6CHE9

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000969001-273Protein N-terminal and lysine N-methyltransferase EFM7

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region1-32Disordered
Compositional bias10-32Basic and acidic residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    273
  • Mass (Da)
    30,729
  • Last updated
    2004-08-16 v1
  • MD5 Checksum
    DD28AD847D04FE01ACC47FC3E7701086
MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLWGHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADLLYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELIEMSGGTGYDLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGFESEKLFELKYYPMFEEEEETKELRSMVFGYMLTLKE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias10-32Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR382127
EMBL· GenBank· DDBJ
CAG83839.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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