Q6AXY7 · PR38B_RAT
- ProteinPre-mRNA-splicing factor 38B
- GenePrpf38b
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids542 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
May be required for pre-mRNA splicing.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | precatalytic spliceosome | |
Biological Process | mRNA processing | |
Biological Process | RNA splicing |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended namePre-mRNA-splicing factor 38B
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionQ6AXY7
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for initiator methionine, modified residue, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Initiator methionine | 1 | Removed | ||||
Sequence: M | ||||||
Modified residue | 2 | N-acetylalanine | ||||
Sequence: A | ||||||
Chain | PRO_0000287237 | 2-542 | Pre-mRNA-splicing factor 38B | |||
Sequence: ANNSPALTGNSQPQHQAAAAVVQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGVEEIDRHIERRRSRSPRRSLSPRRSPRRSRSRSHHRDGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSLDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKDRGNDRERDRERSRERSKEQRSRGEGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKDKASKHKNESKEKSNKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKRDHDSKDQSDRQDHQRSQSVEPESQEKEHKNKDETV | ||||||
Modified residue | 5 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 227 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 288 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 290 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 318 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 320 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 446 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 471 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 473 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 479 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 523 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 525 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 530 | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-24 | Disordered | ||||
Sequence: MANNSPALTGNSQPQHQAAAAVVQ | ||||||
Compositional bias | 232-257 | Basic and acidic residues | ||||
Sequence: QIKTRPRKIKKDGKEGVEEIDRHIER | ||||||
Region | 232-542 | Disordered | ||||
Sequence: QIKTRPRKIKKDGKEGVEEIDRHIERRRSRSPRRSLSPRRSPRRSRSRSHHRDGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSLDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKDRGNDRERDRERSRERSKEQRSRGEGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKDKASKHKNESKEKSNKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKRDHDSKDQSDRQDHQRSQSVEPESQEKEHKNKDETV | ||||||
Compositional bias | 258-282 | Basic residues | ||||
Sequence: RRSRSPRRSLSPRRSPRRSRSRSHH | ||||||
Compositional bias | 283-329 | Basic and acidic residues | ||||
Sequence: RDGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSLDRGLDRRR | ||||||
Coiled coil | 292-323 | |||||
Sequence: DRELEREKERQRLEREAKEREKERRRSRSLDR | ||||||
Compositional bias | 344-415 | Basic and acidic residues | ||||
Sequence: DRKGDRRDRDREREKENERGRRRDRDYDKDRGNDRERDRERSRERSKEQRSRGEGEEKKHKEDKEDRRHRDD | ||||||
Compositional bias | 416-452 | Basic residues | ||||
Sequence: KKESKKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKD | ||||||
Compositional bias | 453-470 | Basic and acidic residues | ||||
Sequence: KASKHKNESKEKSNKRSR | ||||||
Compositional bias | 477-542 | Basic and acidic residues | ||||
Sequence: TGSVEKRKREHSPSREKSRKRSRSQDRSHKRDHDSKDQSDRQDHQRSQSVEPESQEKEHKNKDETV |
Sequence similarities
Belongs to the PRP38 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length542
- Mass (Da)63,932
- Last updated2004-09-13 v1
- Checksum76165E893CA166C5
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8I6G9I2 | A0A8I6G9I2_RAT | Prpf38b | 484 | ||
A0A8I6GHP1 | A0A8I6GHP1_RAT | Prpf38b | 93 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 232-257 | Basic and acidic residues | ||||
Sequence: QIKTRPRKIKKDGKEGVEEIDRHIER | ||||||
Compositional bias | 258-282 | Basic residues | ||||
Sequence: RRSRSPRRSLSPRRSPRRSRSRSHH | ||||||
Compositional bias | 283-329 | Basic and acidic residues | ||||
Sequence: RDGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSLDRGLDRRR | ||||||
Compositional bias | 344-415 | Basic and acidic residues | ||||
Sequence: DRKGDRRDRDREREKENERGRRRDRDYDKDRGNDRERDRERSRERSKEQRSRGEGEEKKHKEDKEDRRHRDD | ||||||
Compositional bias | 416-452 | Basic residues | ||||
Sequence: KKESKKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKD | ||||||
Compositional bias | 453-470 | Basic and acidic residues | ||||
Sequence: KASKHKNESKEKSNKRSR | ||||||
Compositional bias | 477-542 | Basic and acidic residues | ||||
Sequence: TGSVEKRKREHSPSREKSRKRSRSQDRSHKRDHDSKDQSDRQDHQRSQSVEPESQEKEHKNKDETV |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC079264 EMBL· GenBank· DDBJ | AAH79264.1 EMBL· GenBank· DDBJ | mRNA |