Q69472 · Q69472_HHV1
- ProteinEnvelope glycoprotein K
- GeneUL53
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids338 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | host cell endosome membrane | |
Cellular Component | host cell plasma membrane | |
Cellular Component | plasma membrane | |
Cellular Component | viral envelope | |
Biological Process | fusion of viral membrane with host outer nuclear membrane | |
Biological Process | positive regulation of syncytium formation by virus |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameEnvelope glycoprotein K
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageViruses > Duplodnaviria > Heunggongvirae > Peploviricota > Herviviricetes > Herpesvirales > Orthoherpesviridae > Alphaherpesvirinae > Simplexvirus > Simplexvirus humanalpha1
- Virus hosts
Accessions
- Primary accessionQ69472
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Host Golgi apparatus membrane ; Multi-pass membrane protein
Host cell membrane ; Multi-pass membrane protein
Host endosome membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 7-26 | Helical | |||
Transmembrane | 119-139 | Helical | |||
Transmembrane | 213-238 | Helical | |||
Transmembrane | 244-271 | Helical | |||
Transmembrane | 307-327 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Interacts (via UL20 interaction region) with protein UL20 (via N-terminus); this interaction probably plays a role in the coordinate transport of protein UL20 and gK to the trans-Golgi network (TGN), and is required for the cell surface expression of gK.
Family & Domains
Sequence similarities
Belongs to the alphaherpesvirinae glycoprotein K family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length338
- Mass (Da)37,575
- Last updated1996-11-01 v1
- Checksum3FED48AC65E53F8A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U14422 EMBL· GenBank· DDBJ | AAB60558.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EF157323 EMBL· GenBank· DDBJ | ABM52982.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EF157326 EMBL· GenBank· DDBJ | ABM52985.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JQ673480 EMBL· GenBank· DDBJ | AFE62882.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JQ780693 EMBL· GenBank· DDBJ | AFI23645.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KM222721 EMBL· GenBank· DDBJ | AJE59999.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KM222722 EMBL· GenBank· DDBJ | AJE60070.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KM222723 EMBL· GenBank· DDBJ | AJE60141.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KT425110 EMBL· GenBank· DDBJ | ALM22845.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KT899744 EMBL· GenBank· DDBJ | ALO18651.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KT887224 EMBL· GenBank· DDBJ | ALO18727.1 EMBL· GenBank· DDBJ | Genomic DNA |