Q68EH8 · FAD1_DANRE
- ProteinFAD synthase
- Geneflad1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids497 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
Catalytic activity
- ATP + FMN + H+ = diphosphate + FAD
Cofactor
Pathway
Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | FMN adenylyltransferase activity | |
Biological Process | FAD biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFAD synthase
- EC number
- Alternative names
Including 2 domains:
- Recommended nameMolybdenum cofactor biosynthesis protein-like region
- Recommended nameFAD synthase region
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ68EH8
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000302740 | 1-497 | FAD synthase | |||
Sequence: MAQNCNTSSTQKNGSATAAILIIGDEILKGHTVDTNSAFLCRGLRKLGITVERITVVPDVQEVIAKEVSQLSSTVTHLITSGGIGPTHDDVTFESVAMAFGEELYAHPEMTKLVEGFFGTVTSDSAPMKLAMVPASAKLNFGIDPQTGQRNRFPLVSVHNVYIFPGIPSLLEKSFNGLSHLFSGSGTTFHTREVFVNADETEIAQSLSKLQAGWGKRVSLGSYPDWLSNYHRVRLVLDTDSVEEVERARTQLIEELPKGSVVPLVTDPISVAAQEVYSLSKSETQLGKKVAAALGTIEMALDKYSVNEICVGFNGGKDCTALLHLYYAALKRRYPDGKDRLKALYIRIVSPFPEMERFLQDTIKRYDLELFSVEGSIRQALNEVKERRPDLRAVLMGTRRTDPYSHTLTPFCPTDPGWPDYMRVNPLLEWTYHDIWSFLRTLYVPYCILYDKGYTSLGSMDNSYRNPSLKMVDERGATRYKPAYMLENEEEERNSRE |
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 19-110 | Molybdenum cofactor biosynthesis protein-like | ||||
Sequence: AILIIGDEILKGHTVDTNSAFLCRGLRKLGITVERITVVPDVQEVIAKEVSQLSSTVTHLITSGGIGPTHDDVTFESVAMAFGEELYAHPEM | ||||||
Region | 308-465 | FAD synthase | ||||
Sequence: EICVGFNGGKDCTALLHLYYAALKRRYPDGKDRLKALYIRIVSPFPEMERFLQDTIKRYDLELFSVEGSIRQALNEVKERRPDLRAVLMGTRRTDPYSHTLTPFCPTDPGWPDYMRVNPLLEWTYHDIWSFLRTLYVPYCILYDKGYTSLGSMDNSYR |
Domain
The molybdenum cofactor biosynthesis protein-like region may not be functional.
Sequence similarities
In the N-terminal section; belongs to the MoaB/Mog family.
In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length497
- Mass (Da)55,610
- Last updated2004-10-11 v1
- ChecksumD71C34BE8FA99DFF
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0R4INK4 | A0A0R4INK4_DANRE | flad1 | 614 | ||
A0A8M2BH00 | A0A8M2BH00_DANRE | flad1 | 521 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC080254 EMBL· GenBank· DDBJ | AAH80254.1 EMBL· GenBank· DDBJ | mRNA |