Q68CX0 · Q68CX0_HUMAN
- ProteinTransporter
- GeneDKFZp761I0921
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids721 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- L-alanine(in) + Na+(in) = L-alanine(out) + Na+(out)L-alanine (in)CHEBI:57972
+ Na+ (in)CHEBI:29101= L-alanine (out)CHEBI:57972+ Na+ (out)CHEBI:29101 - L-asparagine(in) + Na+(in) = L-asparagine(out) + Na+(out)
- L-cysteine(in) + Na+(in) = L-cysteine(out) + Na+(out)
- L-glutamine(in) + Na+(in) = L-glutamine(out) + Na+(out)
- L-isoleucine(in) + Na+(in) = L-isoleucine(out) + Na+(out)
- L-leucine(in) + Na+(in) = L-leucine(out) + Na+(out)
- L-methionine(in) + Na+(in) = L-methionine(out) + Na+(out)
- L-phenylalanine(in) + Na+(in) = L-phenylalanine(out) + Na+(out)
- L-pipecolate(in) + Na+(in) = L-pipecolate(out) + Na+(out)
- L-proline(in) + Na+(in) = L-proline(out) + Na+(out)
- L-serine(in) + Na+(in) = L-serine(out) + Na+(out)
- L-threonine(in) + Na+(in) = L-threonine(out) + Na+(out)
- L-valine(in) + Na+(in) = L-valine(out) + Na+(out)
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 67 | Na+ 1 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 70 | Na+ 1 (UniProtKB | ChEBI) | ||||
Sequence: V | ||||||
Binding site | 74 | Na+ 1 (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 332 | Na+ 1 (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 461 | Na+ 1 (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 465 | Na+ 1 (UniProtKB | ChEBI) | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | proline:sodium symporter activity | |
Biological Process | L-leucine transport | |
Biological Process | neurotransmitter transport |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameTransporter
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ68CX0
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 91-112 | Helical | ||||
Sequence: LLPYLILLMVIGIPLFFLELSV | ||||||
Transmembrane | 133-160 | Helical | ||||
Sequence: GIGFASCVVCYFVALYYNVIIGWSLFYF | ||||||
Transmembrane | 215-235 | Helical | ||||
Sequence: LNWKMTICLLAAWVMVCLAMI | ||||||
Transmembrane | 244-265 | Helical | ||||
Sequence: IIYFSSLFPYVVLICFLIRAFL | ||||||
Transmembrane | 293-314 | Helical | ||||
Sequence: AATQVFFALGLGFGGVIAFSSY | ||||||
Transmembrane | 326-347 | Helical | ||||
Sequence: VLVSFINFFTSVLATLVVFAVL | ||||||
Transmembrane | 449-474 | Helical | ||||
Sequence: FWSVMFFLMLVNLGLGSMFGTIEGIV | ||||||
Transmembrane | 486-504 | Helical | ||||
Sequence: EILTVICCLLAFCIGLIFV | ||||||
Transmembrane | 524-541 | Helical | ||||
Sequence: LLIVVILENIAVCFVYGI | ||||||
Transmembrane | 562-585 | Helical | ||||
Sequence: YMWKYISPLMLLSLLIASVVNMGL | ||||||
Transmembrane | 605-630 | Helical | ||||
Sequence: YPTWGLVVCVSLVVFAILPVPVVFIV |
Keywords
- Cellular component
PTM/Processing
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 32-51 | Disordered | ||||
Sequence: VDGQEEKDTDVEEGSEVEDE |
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length721
- Mass (Da)80,824
- Last updated2004-10-11 v1
- ChecksumFD7BC18FFFC3B4A3
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: R |