The full-ORF clone resource of the German cDNA consortium.Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A.[...], Schupp I.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLU-67 AND ASP-111TissueEndometrial adenocarcinoma, Fetal kidneyCategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBMC Genomics 8:399-399 (2007)Cited in99+
The DNA sequence and biological annotation of human chromosome 1.Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K.[...], Bentley D.R.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 441:315-321 (2006)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueCervixCategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAnal. Chem. 81:4493-4501 (2009)Cited in99+99+Mapped to18
Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBMC Syst. Biol. 5:17-17 (2011)Cited in99+99+
Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.Ahmad Y., Boisvert F.M., Lundberg E., Uhlen M., Lamond A.I.View abstractCited forSUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]CategorySubcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Proteomics 11:M111.013680.01-M111.013680.15 (2012)Cited in18
Toward a comprehensive characterization of a human cancer cell phosphoproteome.Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinoma, ErythroleukemiaCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Proteome Res. 12:260-271 (2013)Cited in99+99+
MiR-195 affects cell migration and cell proliferation by down-regulating DIEXF in Hirschsprung's disease.Lei H., Tang J., Li H., Zhang H., Lu C., Chen H., Li W., Xia Y., Tang W.View abstractCited forFUNCTION, TISSUE SPECIFICITY, INDUCTION BY MIR195CategoriesFunction, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBMC Gastroenterol. 14:123-123 (2014)Cited in1Mapped to4
Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3.Guan Y., Huang D., Chen F., Gao C., Tao T., Shi H., Zhao S., Liao Z., Lo L.J.[...], Peng J.View abstractCited forFUNCTION, INTERACTION WITH CAPN3, PHOSPHORYLATION AT SER-50; SER-58 AND SER-62CategoriesFunction, PTM / Processing, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS Biol. 14:e1002555-e1002555 (2016)Cited in4
Def defines a conserved nucleolar pathway that leads p53 to proteasome- independent degradation.Tao T., Shi H., Guan Y., Huang D., Chen Y., Lane D.P., Chen J., Peng J.View abstractCited forVARIANTS GLU-67 AND ASP-111, CHARACTERIZATION OF VARIANTS GLU-67 AND ASP-111, FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH CAPN3CategoriesFunction, Sequences, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Res. 23:620-634 (2013)Cited in39Mapped to9
Nucleolin functions in the first step of ribosomal RNA processing.Ginisty H., Amalric F., Bouvet P.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCEMBO J 17:1476-1486 (1998)Mapped to51
Tissue and cancer-specific expression of DIEXF is epigenetically mediated by an Alu repeat.Martin B., Pappa S., Diez-Villanueva A., Mallona I., Custodio J., Barrero M.J., Peinado M.A., Jorda M.View abstractAnnotationTissue and cancer-specific expression of DIEXF is epigenetically mediated by an Alu repeat.CategoriesFunction, ExpressionSourceGeneRif: 27042PubMedEurope PMCEpigenetics 15:765-779 (2020)Mapped to5
The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.Tao T., Sondalle S.B., Shi H., Zhu S., Perez-Atayde A.R., Peng J., Baserga S.J., Look A.T.View abstractAnnotationDEF is highly expressed in human neuroblastoma and its depletion in human neuroblastoma cell lines induces apoptosis.CategoryFunctionSourceGeneRif: 27042PubMedEurope PMCOncogene 36:3852-3867 (2017)Cited in1Mapped to5
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.Hein M.Y., Hubner N.C., Poser I., Cox J., Nagaraj N., Toyoda Y., Gak I.A., Weisswange I., Mansfeld J.[...], Mann M.View abstractCategoryInteractionSourceIntAct: Q68CQ4PubMedEurope PMCCell 163:712-723 (2015)Mapped to99+
hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0.Tomecki R., Labno A., Drazkowska K., Cysewski D., Dziembowski A.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCRNA Biol 12:1010-1029 (2015)Mapped to66
Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.Yoshikawa H., Ishikawa H., Izumikawa K., Miura Y., Hayano T., Isobe T., Simpson R.J., Takahashi N.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCNucleic Acids Res 43:5524-5536 (2015)Mapped to58
A proteome-scale map of the human interactome network.Rolland T., Tasan M., Charloteaux B., Pevzner S.J., Zhong Q., Sahni N., Yi S., Lemmens I., Fontanillo C.[...], Vidal M.View abstractCategoryInteractionSourceIntAct: Q68CQ4PubMedEurope PMCCell 159:1212-1226 (2014)Mapped to99+
The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA.Sloan K.E., Bohnsack M.T., Schneider C., Watkins N.J.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCRNA 20:540-550 (2014)Mapped to51
The first pre-rRNA-processing event occurs in a large complex: analysis by gel retardation, sedimentation, and UV cross-linking.Kass S., Sollner-Webb B.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCMol Cell Biol 10:4920-4931 (1990)Mapped to51
Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA.Preti M., O'Donohue M.F., Montel-Lehry N., Bortolin-Cavaille M.L., Choesmel V., Gleizes P.E.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCNucleic Acids Res 41:4709-4723 (2013)Mapped to99+
Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing.Sloan K.E., Mattijssen S., Lebaron S., Tollervey D., Pruijn G.J., Watkins N.J.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCJ Cell Biol 200:577-588 (2013)Mapped to67
NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.Freed E.F., Prieto J.L., McCann K.L., McStay B., Baserga S.J.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCPLoS Genet. 8:E1002892-E1002892 (2012)Cited in6Mapped to59
The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing.Morello L.G., Coltri P.P., Quaresma A.J., Simabuco F.M., Silva T.C., Singh G., Nickerson J.A., Oliveira C.C., Moore M.J., Zanchin N.I.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCPLoS ONE 6:E29174-E29174 (2011)Cited in2Mapped to62
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.Thomas S.R., Keller C.A., Szyk A., Cannon J.R., Laronde-Leblanc N.A.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCNucleic Acids Res. 39:2445-2457 (2011)Cited in2Mapped to48
5'-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre- rRNA maturation and decay.Wang M., Pestov D.G.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6790689PubMedEurope PMCNucleic Acids Res 39:1811-1822 (2011)Mapped to52