Q67YG7 · SOFL1_ARATH

Function

function

Involved in cytokinin-mediated development (PubMed:20011053, PubMed:29467189).
Together with SOFL2, triggers the endogenous content of specific bioactive cytokinins derived from the biosynthetic intermediates trans-zeatin riboside monophosphate (tZRMP) and N6-(Delta2-isopentenyl)adenosine monophosphate (iPRMP) such as N-glucosides trans-zeatin 7-glucoside (tZ7G), cis-zeatin 7-glucoside (cZ7G) and N6-(Delta2-isopentenyl)adenine 7-glucoside (iP7G) (PubMed:20011053).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Biological Processcytokinin biosynthetic process
Biological Processcytokinin metabolic process
Biological Processcytokinin-activated signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein SOB FIVE-LIKE 1
  • Short names
    AtSOFL1

Gene names

    • Name
      SOFL1
    • ORF names
      F28B23.12
    • Ordered locus names
      At1g26210

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q67YG7
  • Secondary accessions
    • Q681A7
    • Q8LAZ9
    • Q9C665

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Plants missing both SOLF1 and SOLF2 have reduced endogenous cytokinin levels and accumulate lower levels of trans-zeatin riboside monophosphate (tZRMP) and N6-(Delta2-isopentenyl)adenosine monophosphate (iPRMP), biosynthetic intermediates of bioactive cytokinins as well as decreased response to exogenous cytokinin in both callus-formation and inhibition-of-hypocotyl-elongation assays.

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis23Impaired function in cytokinin-mediated development; when associated with R-84.
Mutagenesis84Impaired function in cytokinin-mediated development; when associated with I-23.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 20 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004502491-148Protein SOB FIVE-LIKE 1

Proteomic databases

Expression

Tissue specificity

Predominantly expressed in the vascular tissues of seedlings, developing leaves, flowers and siliques, but barely detectable in roots and stems.

Developmental stage

In seedlings, strong levels in the hydathode region of cotyledons as well as in the upper part of hypocotyls and weak content in the vascular tissue of cotyledons (PubMed:20011053).
In developing leaves, strongly expressed in the midrib of leaf veins, but weak levels in the hydathode regions (PubMed:20011053).
In developing flower buds, accumulates in pistil tips and the vascular tissue of stamens and sepals (PubMed:20011053).
In mature flowers, detected in the vascular bundles between the two anther locules, the central vascular cylinders of the filaments, vascular tissues of tips and bases of the pistils, and sepal vascular tissue (PubMed:20011053).
Also present in tips and bases of developing siliques, and progressively restricted to the vascular tissues at the silique tips (PubMed:20011053).

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, motif, compositional bias.

TypeIDPosition(s)Description
Region1-20Disordered
Motif20-25SOFL-A
Region33-148Disordered
Compositional bias39-76Acidic residues
Motif75-84SOFL-B
Compositional bias108-130Basic and acidic residues

Domain

Domains SOFL-A and SOFL-B are required for function in cytokinin-mediated development.

Sequence similarities

Belongs to the SOFL plant protein family.

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q67YG7-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    148
  • Mass (Da)
    16,249
  • Last updated
    2004-10-11 v1
  • Checksum
    C0DD7F92C3A745E0
MESPRNHGGSEEEEYSSCESGWTMYIEDAFHGNDQSSVVVDDDDDDTQVKEADDGYENDDGDTSDDGGDEESDDSMASDASSGPSNQLPKHINKHAARKNGSKQVYLQKRQHTEKTISNEGEKSDLKARTRTSAASRVQSRGKVSKTK

Q67YG7-2

Sequence caution

The sequence AAG50669.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for sequence conflict, compositional bias.

TypeIDPosition(s)Description
Sequence conflict35in Ref. 3; BAD43473
Compositional bias39-76Acidic residues
Sequence conflict59in Ref. 5; AAM65051
Compositional bias108-130Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC079829
EMBL· GenBank· DDBJ
AAG50669.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002684
EMBL· GenBank· DDBJ
AEE30661.1
EMBL· GenBank· DDBJ
Genomic DNA
AK175479
EMBL· GenBank· DDBJ
BAD43242.1
EMBL· GenBank· DDBJ
mRNA
AK175710
EMBL· GenBank· DDBJ
BAD43473.1
EMBL· GenBank· DDBJ
mRNA
AK176501
EMBL· GenBank· DDBJ
BAD44264.1
EMBL· GenBank· DDBJ
mRNA
BT024679
EMBL· GenBank· DDBJ
ABD57504.1
EMBL· GenBank· DDBJ
mRNA
AY087508
EMBL· GenBank· DDBJ
AAM65051.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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