Q67WM9 · OS9_ORYSJ
- ProteinProtein OS-9 homolog
- GeneOS9
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids298 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 130 | a mannooligosaccharide derivative (UniProtKB | ChEBI) | ||||
Sequence: W | ||||||
Binding site | 131 | a mannooligosaccharide derivative (UniProtKB | ChEBI) | ||||
Sequence: W | ||||||
Binding site | 143 | a mannooligosaccharide derivative (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Binding site | 202 | a mannooligosaccharide derivative (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 208 | a mannooligosaccharide derivative (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 228 | a mannooligosaccharide derivative (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 234 | a mannooligosaccharide derivative (UniProtKB | ChEBI) | ||||
Sequence: Y |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum lumen | |
Molecular Function | carbohydrate binding | |
Biological Process | endoplasmic reticulum unfolded protein response | |
Biological Process | response to salt stress | |
Biological Process | retrograde protein transport, ER to cytosol |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameProtein OS-9 homolog
- Short namesOsOS9
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionQ67WM9
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, glycosylation, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-25 | |||||
Sequence: MGLAGGARVVLFVVAAAAAAALTAA | ||||||
Chain | PRO_0000431277 | 26-298 | Protein OS-9 homolog | |||
Sequence: ADQIFTSSGAPFGRNSREPRYHVEFHPVDAPFNPENGQESVPMTSHVGKHYTCFLPVEETKTMKSIIPQNATNVIIESERRVKPKDPDELLEILKDQCFYRHEGWWSYEFCYYGKIRQVHVEGEKVIQEYVLGEYDADATDAYYENQTSDSADEDDNLIDTSKRYHVHLYTNGTVCDLTDMPRETEVRFVCSEPTVVISSIKEISSCKYVLTVQSPMLCKNPLFQQEKRTLSIHCNELLAEAEATVDDDSLPKEAQIIIPDPDGLHNYAAYAT | ||||||
Glycosylation | 95 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 123↔136 | |||||
Sequence: CFYRHEGWWSYEFC | ||||||
Glycosylation | 171 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 197 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 201↔232 | |||||
Sequence: CDLTDMPRETEVRFVCSEPTVVISSIKEISSC | ||||||
Disulfide bond | 216↔244 | |||||
Sequence: CSEPTVVISSIKEISSCKYVLTVQSPMLC |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 121-246 | MRH | ||||
Sequence: DQCFYRHEGWWSYEFCYYGKIRQVHVEGEKVIQEYVLGEYDADATDAYYENQTSDSADEDDNLIDTSKRYHVHLYTNGTVCDLTDMPRETEVRFVCSEPTVVISSIKEISSCKYVLTVQSPMLCKN |
Sequence similarities
Belongs to the OS-9 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length298
- Mass (Da)33,439
- Last updated2004-10-11 v1
- Checksum73B0E5B070415475
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0P0WZ99 | A0A0P0WZ99_ORYSJ | Os06g0644800 | 174 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP003568 EMBL· GenBank· DDBJ | BAD37440.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP008212 EMBL· GenBank· DDBJ | BAH93656.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP014962 EMBL· GenBank· DDBJ | BAS98847.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CM000143 EMBL· GenBank· DDBJ | EAZ37805.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK109442 EMBL· GenBank· DDBJ | BAG98751.1 EMBL· GenBank· DDBJ | mRNA |