Q66M49 · Q66M49_PHERA
- Proteinperoxidase
- GenePOX1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids265 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- 2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 calcium ions per subunit.
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
Features
Showing features for site, active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 68 | Transition state stabilizer | ||||
Sequence: R | ||||||
Active site | 72 | Proton acceptor | ||||
Sequence: H | ||||||
Binding site | 73 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 76 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: V | ||||||
Binding site | 78 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 80 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 82 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 94 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 169 | substrate | ||||
Sequence: P | ||||||
Binding site | 199 | Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 200 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | heme binding | |
Molecular Function | lactoperoxidase activity | |
Molecular Function | metal ion binding | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | response to oxidative stress |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameperoxidase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Lamiales > Orobanchaceae > Orobancheae > Phelipanche
Accessions
- Primary accessionQ66M49
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-30 | |||||
Sequence: MENKKIYQLCCCALAILSLILFLSSTPTQA | ||||||
Chain | PRO_5004268950 | 31-265 | peroxidase | |||
Sequence: QLSPTFYSRTCRNAPTIIRNSIRRAISRERRMAASLIRLHFHDCFVQGCDASILLDETPSIQSEKTAFPNVNSARGFDVIEAVKREVERICPRVVSCADILTLAARDASVAVGGPTWTVRLGRRDSTAANRGEANTDLPSPFAGLQALITAFADKGLSETDMVALSGSHTLGQAQCFLFRARIYSNGTDIDPNFARNRRRQCPQTSGNSKRHITLKTCHNHYLAIIFFLGLLYSK | ||||||
Disulfide bond | 41↔121 | |||||
Sequence: CRNAPTIIRNSIRRAISRERRMAASLIRLHFHDCFVQGCDASILLDETPSIQSEKTAFPNVNSARGFDVIEAVKREVERIC | ||||||
Disulfide bond | 74↔79 | |||||
Sequence: CFVQGC | ||||||
Disulfide bond | 206↔232 | |||||
Sequence: CFLFRARIYSNGTDIDPNFARNRRRQC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 31-265 | Plant heme peroxidase family profile | ||||
Sequence: QLSPTFYSRTCRNAPTIIRNSIRRAISRERRMAASLIRLHFHDCFVQGCDASILLDETPSIQSEKTAFPNVNSARGFDVIEAVKREVERICPRVVSCADILTLAARDASVAVGGPTWTVRLGRRDSTAANRGEANTDLPSPFAGLQALITAFADKGLSETDMVALSGSHTLGQAQCFLFRARIYSNGTDIDPNFARNRRRQCPQTSGNSKRHITLKTCHNHYLAIIFFLGLLYSK |
Sequence similarities
Belongs to the peroxidase family. Ascorbate peroxidase subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length265
- Mass (Da)29,315
- Last updated2005-08-02 v2
- ChecksumDB3196278540493D