Q66I06 · GGACB_DANRE
- ProteinGamma-glutamylaminecyclotransferase B
- Geneggact.2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids191 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
May contribute to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.
Catalytic activity
- epsilon-(gamma-L-glutamyl)-L-lysine = 5-oxo-L-proline + L-lysine
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7-10 | substrate | |||
Active site | 82 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | gamma-glutamylaminecyclotransferase activity | |
Biological Process | cellular modified amino acid catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGamma-glutamylaminecyclotransferase B
- EC number
- Short namesGGACT B
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ66I06
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000320206 | 1-191 | Gamma-glutamylaminecyclotransferase B | ||
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 155-180 | Polar residues | |||
Region | 155-191 | Disordered | |||
Sequence similarities
Belongs to the gamma-glutamylcyclotransferase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length191
- Mass (Da)22,015
- Last updated2004-10-11 v1
- MD5 Checksum95500CAE267AA84BD163E672344C9899
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 155-180 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC081599 EMBL· GenBank· DDBJ | AAH81599.1 EMBL· GenBank· DDBJ | mRNA |