Q63QE9 · PRMC_BURPS
- ProteinRelease factor glutamine methyltransferase
- GeneprmC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids285 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Catalytic activity
- L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 119-123 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 142 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 175 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 191 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 191-194 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nucleic acid binding | |
Molecular Function | protein-(glutamine-N5) methyltransferase activity | |
Molecular Function | protein-glutamine N-methyltransferase activity | |
Biological Process | peptidyl-glutamine methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRelease factor glutamine methyltransferase
- EC number
- Short namesRF MTase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > pseudomallei group
Accessions
- Primary accessionQ63QE9
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000414506 | 1-285 | Release factor glutamine methyltransferase | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length285
- Mass (Da)30,250
- Last updated2004-10-25 v1
- Checksum0F3239D23E5AC886
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX571965 EMBL· GenBank· DDBJ | CAH37085.1 EMBL· GenBank· DDBJ | Genomic DNA |